Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer [PDF]
, 2014 The RUNX1 transcription factor is widely recognised for its tumour suppressor effects in leukaemia. Recently a putative link to breast cancer has started to emerge, however the function of RUNX1 in breast cancer is still unknown.
Blyth, Karen +9 more
core +10 more sources
A prospective randomized trial of FK506-based immunosuppression after renal transplantation [PDF]
, 1995 A group of 204 adult patients was entered into a prospective, randomized trial comparing FK506/pred-nisone with FK506/azathioprine/prednisone after renal transplantation between August 1, 1991 and October 11,1992.
Demetris, AJ +12 more
core +1 more source
Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]
, 2019 BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M +9 more
core +4 more sources
Phospho-Akt expression is high in a subset of triple negative breast cancer patients [PDF]
, 2014 The most commonly used biomarkers to predict the response of breast cancer patients to therapy are oestrogen receptor (ER), progesterone receptor (PgR), and human epidermal growth factor receptor 2 (HER2).
Baldacchino, Shawn +6 more
core +1 more source
A prospective randomized trial of tacrolimus and prednisone versus tacrolimus, prednisone, and mycophenolate mofetil in primary adult liver transplant recipients: An interim report [PDF]
, 1998 Background. Tacrolimus (Tac) and mycophenolate mofetil (MMF) are newly approved immunosuppressive agents. However, the safety and efficacy of the combination of MMF and Tac in primary liver transplantation has not been determined. Methods.
Demetris, J +8 more
core +1 more source
Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models. [PDF]
, 2017 Metastasis is a major cause of mortality for cancer patients and remains as the greatest challenge in cancer therapy. Driven by multiple factors, metastasis may not be controlled by the inhibition of single target.
DeVere White, Ralph W +11 more
core +1 more source
Time to AIDS from 1992 to 1999 in HIV-1-Infected Subjects with Known Date of Infection. [PDF]
, 2002 To estimate the change in AIDS incubation time during three periods characterized by different availability of antiretroviral treatments, data from the French Hospital Database on HIV of 4702 HIV-1-positive subjects with a documented date of infection ...
Bentata, M +5 more
core +2 more sources
Neoadjuvant therapy for breast cancer [PDF]
, 2019 Objective: To evaluate the frequency of neoadjuvant therapy (NT) in women with stage I–III breast cancer in Italy and whether it is influenced by biological characteristics, screening history, and geographic area.
Carrozzi G. +10 more
core +1 more source
Single-inhaler triple therapy in patients with chronic obstructive pulmonary disease:a systematic review [PDF]
, 2019 Background Guidelines recommend that treatment with a long-acting β2 agonist (LABA), a long-acting muscarinic antagonist (LAMA), and inhaled corticosteroids (ICS), i.e.
Chalmers, James D. +6 more
core +5 more sources
, 2014 AIM: To investigate the predictability of interleukin-28B single nucleotide polymorphism rs12979860 with respect to sustained virological response (SVR) in chronically hepatitis C virus (HCV) genotype-1 patients treated with a protease-inhibitor and ...
Amanzada, Ahmad +3 more
core +1 more source