Results 41 to 50 of about 459,163 (313)

Triple drug therapy in testicular tumors [PDF]

open access: yesCancer, 1969
Thirty-four patients with disseminated choriocarcinoma, embryonal cell carcinoma, and teratocarcinoma of the testis were treated with triple drug therapy—chlorambucil, methotrexate, and actinomycin D as employed by Li et al. Although two-thirds of patients with measurable lesions had at least a 50% regression, reactivation usually occurred within 3 ...
F J, Ansfield   +3 more
openaire   +2 more sources

Single-inhaler triple therapy in patients with chronic obstructive pulmonary disease:a systematic review [PDF]

open access: yes, 2019
Background Guidelines recommend that treatment with a long-acting β2 agonist (LABA), a long-acting muscarinic antagonist (LAMA), and inhaled corticosteroids (ICS), i.e.
Chalmers, James D.   +6 more
core   +5 more sources

Triple inhaler therapy for COPD [PDF]

open access: yesThorax, 2015
The randomised controlled trial (GLISTEN) by Frith et al 1 showed significant improvements in trough FEV1, health-related quality of life and rescue medication when long-acting muscarinic antagonists (LAMA: as either tiotropium or glycopyrronium) were added to inhaled corticosteroid/long-acting beta-agonist (ICS/LABA: as fluticasone/salmeterol) in 773 ...
openaire   +2 more sources

Triple Therapy for COPD: Historical Perspective and Current Controversies

open access: yesBarcelona Respiratory Network Reviews, 2023
The use of a combination of three inhaled drugs has recently been established as the first choice for some patients in the algorithm for the treatment of chronic obstructive pulmonary disease. In this review, we aim to give an overview of the development
Jose L. López-Campos
doaj   +1 more source

Time to AIDS from 1992 to 1999 in HIV-1-Infected Subjects with Known Date of Infection. [PDF]

open access: yes, 2002
To estimate the change in AIDS incubation time during three periods characterized by different availability of antiretroviral treatments, data from the French Hospital Database on HIV of 4702 HIV-1-positive subjects with a documented date of infection ...
Bentata, M   +5 more
core   +2 more sources

Time-trends and treatment gaps in the antithrombotic management of patients with atrial fibrillation after percutaneous coronary intervention: Insights from the CHUM AF-STENT Registry. [PDF]

open access: yes, 2020
BACKGROUND: The management of atrial fibrillation and flutter (AF) patients undergoing percutaneous coronary intervention (PCI) has undergone a rapid recent evolution. In 2016, the Canadian Cardiovascular Society (CCS) published expert recommendations to
Boivin-Proulx, L-A   +7 more
core   +1 more source

Impact of triple therapy on mortality in COPD

open access: yesBreathe, 2023
Only a few therapies have been shown to prolong survival in specific patients with COPD. In recent years, the IMPACT and the ETHOS trials suggested that triple therapy (a combination of inhaled corticosteroid (ICS), long-acting muscarinic antagonist (LAMA) and long-acting β2-agonist (LABA) given in a single inhaler) may reduce mortality compared with ...
Thibaud Soumagne   +4 more
openaire   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Comparative Study on Effect of Rabeprazole Versus Omeprazole in Acid-peptic Disorder with Helicobacter pylori Infection

open access: yesJournal of Nepal Health Research Council, 2020
Background: Gastritis is one of the common diseases, which is frequently caused by Helicobacter pylori. Triple therapy has resulted significant decrease in morbidity and complications.
Sukh Bahadur Gurung   +3 more
doaj   +1 more source

Boceprevir in combination with HIV protease inhibitors in patients with advanced fibrosis-altered drug-drug interactions? [PDF]

open access: yes, 2012
In HIV/HCV co-infected patients improved treatment outcomes have been reported for the HCV protease inhibitors (PIs) boceprevir (BOC) and telaprevir (TVR), reaching SVR rates of up to 70% in pilot trials.
C Boesecke   +4 more
core   +1 more source

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