HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion [PDF]
, 2014 This article has been made available through the Brunel Open Access Publishing Fund.PTK6/Brk is a non-receptor tyrosine kinase overexpressed in cancer.
Blokland, NJG +8 more
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Clinical trial of FK 506 immunosuppression in adult cardiac transplantation [PDF]
, 1992 The new immunosuppressive agent FK 506 was used as primary immunotherapy in conjunction with low-dose steroids and azathioprine in 72 patients subsequent to orthotopic cardiac transplantation.
Armitage +17 more
core +1 more source
Co-producing healthcare in a volume vs. value-based healthcare system: perspective of a parent of a patient and a health professions’ educator [PDF]
, 2019 The Institute for Healthcare Improvement’s Triple Aim framework represents an approach to optimizing a health system’s performance by focusing on improving the patient experience of care, improving the health of populations, and reducing healthcare costs.
Caron, Rosemary M.
core +3 more sources
DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. [PDF]
, 2017 Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature.
Berry, Don +20 more
core +2 more sources
Fused-core HPLC method development implemented in a short-term stability study of Triple IT solution [PDF]
, 2011 For the majority of children with acute lymphoblastic leukemia (ALL), treatment consists in part of a triple intrathecal (Triple IT) therapy, i.e. a combination of cytarabine (CB), methotrexate (MTX) and methylprednisolone sodium succinate (MPSS) [1 ...
Bauters, Tieneke +7 more
core
In vivo E2F reporting reveals efficacious schedules of MEK1/2–CDK4/6 targeting and mTOR–s6 resistance mechanisms [PDF]
, 2018 Targeting cyclin-dependent kinases 4/6 (CDK4/6) represents a therapeutic option in combination with BRAF inhibitor and/or MEK inhibitor (MEKi) in melanoma; however, continuous dosing elicits toxicities in patients. Using quantitative and temporal in vivo
Aplin, Andrew E. +14 more
core +1 more source
Methylphenidate, Bupropion, and SSRI Triple Therapy [PDF]
, 2012 Methylphenidate and bupropion have been demonstrated as being effective adjuncts to serotonin reuptake inhibitors in the treatment of depression (1,2). The use of these medications in case of a depressed patient whose condition was resistant to several ...
Bobo, William, M.D.
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Assessment and analysis of H.pylori infection treatment strategies of St. Vincent Hospital\u27s family and internal medicine clinics [PDF]
, 2019 Helicobacter pylori is a gram-negative bacteria that is responsible for causing chronic gastritis, ulcers in the stomach and intestine, and eventually even gastric lymphoma or cancer.
Orr, Rebecca
core +1 more source
Impact of creatinine clearance on helicobacter pylori eradication rate in patients with peptic ulcer disease [PDF]
, 2015 Introduction. Gastrointestinal complaints are common in patients with kidney failure. The aim of this study was to investigate the effect of creatinine clearance on Helicobacter pylori (HP) eradication rate in patients with peptic ulcer disease ...
Alimadadi, M. +6 more
core
An Open-Label Randomized Controlled Trial Comparing the Efficacy and Safety of a 7-Day Triple Therapy With Bismuth Versus 14-Day Standard Triple Therapy for Helicobacter pylori Eradication in Children and Adolescents. [PDF]
HelicobacterŠterbenc A +3 more
europepmc +1 more source