Results 101 to 110 of about 1,723 (256)

A 141-GHz Integrated Quasi-Optical Slot Antenna Tripler

, 1999
We present a quasi-optical frequency tripler with heterostructure barrier varactor (HBV) diodes soldered across two slot antennas and located at the focal plane of a dielectric lens.
Dillner, Lars, Hollung, Stein, Stake, Jan, Kollberg, Erik   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A 300 GHz Active Frequency Tripler in Transferred-Substrate InP DHBT Technology

, 2019
This paper presents a monolithic integrated active frequency tripler implemented in an InP double heterojunction bipolar transistor (DHBT) transferred-substrate (TS) technology.
T. K. Johansen, R. Doerner, Heinrich, W., W. Heinrich, S. Boppel, V. Krozer, Johansen, Tom Keinicke, Boppel, S., Doerner, R., Krozer, Viktor, M. Hossain, Hossain, M.   +11 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Prospective Evaluation of Range of Motion in Acute ACL Reconstruction Using Patellar Tendon Autograft

Orthopaedic Journal of Sports Medicine, 2019
Background: Optimal timing of anterior cruciate ligament (ACL) reconstruction has been a topic of controversy. Reconstruction has historically been delayed for at least 3 weeks, given previous studies reporting a high risk of postoperative arthrofibrosis
Mitchell C. Harris MD, Connor Venrick BS, Adam C. Hines MD, Jay B. Cook MD, Douglas J. Rowles MD, John M. Tokish MD, Craig R. Bottoni MD   +6 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

High efficiency W-band HBV Tripler and Device Reliability Studies

, 2006
We report on the design and MBE-growth of heterostructure barrier varactor (HBV) diode materials. The quality and performance of in-house HBV materials are presented.
Emadi, Arezoo, Sadeghi, Mahdad, Frederic, Bue, Vellas, Nicolas, Stake, Jan, Emadi, T. Arezoo, Vukusic, Josip, Alderman, Byron, Bryllert, Tomas   +8 more
core   +1 more source

A W-band GCPW MMIC Diode Tripler [PDF]

, 2002
A W-band GCPW (grounded coplanar waveguide) MMIC diode tripler using GaAs PHEMT process is developed. An anti-parallel diode pair is used to produce third harmonic signal and a GCPW band pass filter is used to reject the spurious signal.
Morgan, Matthew, Wang, Huei, Gaier, Todd, Lin, Kun-You, Weinreb, Sander   +4 more
core  

High power W-band monolithically integrated tripler

, 2009
We have designed, fabricated and characterized a Heterostructure Barrier Varactor based monolithic tripler at 97 GHz. The original InP host substrate is used as the microstrip waveguide.
Vukusic, Josip,, Olsen, Arne,, Olsen, Arne, Arne Oistein Olsen, Tomas Bryllert, Bryllert, Tomas,, Stake, Jan, Stake, Jan,, Josip Vukusic, Jan Stake, Vukusic, Josip, Bryllert, Tomas   +11 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source