Results 81 to 90 of about 1,037 (193)

Oxidative stress‐driven metabolic reprogramming defines two subtypes of cutaneous melanoma

VIEW, EarlyView.
Cutaneous melanoma exhibits substantial molecular heterogeneity, and metabolic reprogramming may contribute to differences in tumor behavior and treatment response. In this study, we integrated multi‐omics data from SKCM cohorts to identify two metabolism‐associated subtypes with distinct oxidative stress profiles, immune microenvironments, prognostic ...
Qikun Gao, Ziyi Liu, Ying Xu
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

The FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior, Maria Anastasia Doumani, Hao Fu, Jelle van den Bor, Olof Idevall‐Hagren, Aristidis Moustakas   +5 more
wiley   +1 more source

Reliability-oriented design of additively manufactured metallic TPMS lattice structures: from geometry control to defect-tolerant service performance

Frontiers in Mechanical Engineering
Triply periodic minimal surface (TPMS) lattice structures have become an important route for lightweight metallic components because they combine smooth curvature, interconnected pores, and adjustable geometric parameters.
Rongji Tang, Rongji Tang, Rongji Tang, Yunfeng Qi, Yuedong Zou, Liansong Wang, He Kong, Shuo Li, Xianzheng Liu   +8 more
doaj   +1 more source

Influence of degree of conversion on the cytotoxicity of 3D‐printed denture base resins. A scoping review

Journal of Prosthodontics, EarlyView.
Abstract Purpose Evidence regarding the cytotoxicity of 3D‐printed denture base resins and the role of degree of conversion remains limited and heterogeneous. Therefore, this scoping review aimed to map existing in vitro evidence and explore how degree of conversion and post‐processing factors are reported in relation to biological outcomes.
Nathan Felipini Ferreira, João Pedro Justino de Oliveira Limírio, Ana Beatriz de Souza Albergardi, Emilia de Paula, Sebastian Daniel Aguayo Paul, Jéssica Marcela de Luna Gomes   +5 more
wiley   +1 more source

Semi‐Automated μCT‐Based Modeling of Vertebral Bony Endplate Microporosity and Mechanical Properties: Linking Microstructure to Inferred Mechanical Performance

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background The vertebral bony endplate (BEP) plays a role in regulating both mechanical load transfer and nutrient transport to the intervertebral disc, functions strongly influenced by its microstructural porosity. Variations in porosity impact bone strength, elasticity, and solute diffusion, affecting its overall mechanical competence ...
Ahmad Alminnawi, Gabriele Nasello, Katherine B. Crump, Benjamin Gantenbein, Jerome Noailly, Liesbet Geris   +5 more
wiley   +1 more source

Optimization of Triply Periodic Minimal Surface Heat Exchanger to Achieve Compactness, High Efficiency, and Low-Pressure Drop

Energies
With advancements in additive manufacturing (AM) techniques, high-quality triply periodic minimal surface (TPMS) structures can now be produced. TPMS walled heat exchangers (HX) hold significant potential for industrial applications and are receiving ...
Jian Liu, David Cheng, Khin Oo, Wang Pan, Ty-Liyiah McCrimmon, Shuang Bai   +5 more
doaj   +1 more source

Computational Investigation of the Fluidic Properties of Triply Periodic Minimal Surface (TPMS) Structures in Tissue Engineering

Designs
Tissue engineering, a rapidly advancing field in medicine, has made significant strides with the development of artificial tissue substitutes to meet the growing need for organ transplants. Three-dimensional (3D) porous scaffolds are widely utilized in tissue engineering, especially in orthopedic surgery.
Muhammad Noman Shahid, Muhammad Usman Shahid, Shummaila Rasheed, Muhammad Irfan, Muhannad Ahmed Obeidi   +4 more
openaire   +2 more sources

On the Lightweight Potential of Laser Additive Manufactured NiTi Triply Periodic Minimal Sheet Lattices

Advanced Engineering Materials, Volume 28, Issue 15, 5 August 2026.
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo, Shuo Qu, Shiming Gao, Xu Song   +3 more
wiley   +1 more source

Unidirectional Evaporation‐Induced Tunable and Continuous Gradient Composite Structure for Absorption‐Dominant Electromagnetic Interference Shielding

Advanced Science, Volume 13, Issue 45, 13 August 2026.
A continuous conductivity gradient is formed in a porous MXene/melamine foam via directional evaporation, thereby improving impedance matching and enhancing electromagnetic attenuation. The resulting monolithic composite delivers absorption‐dominant EMI shielding with ultralow reflection, offering a simple route toward lightweight EMI shielding ...
Dawei Zhang, Yan Zhang, Baosong Li, Abdallah Kamal, Haider Butt, Kin Liao, Lianxi Zheng   +6 more
wiley   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, Volume 13, Issue 45, 13 August 2026.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source