Results 61 to 70 of about 2,237,494 (278)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Materials & Design, 2018 Functionally Graded Porous Scaffold (FGPS) becomes an attractive candidate for bone graft due to its combination of better mechanical and biological requirements with the scaffold gradient to better mimic host tissue.
Fei Liu +5 more
doaj +1 more source
On the genus of triply periodic minimal surfaces
Journal of Differential Geometry, 2008 we prove the existence of embedded minimal surfaces of arbitrary genus g 3 in any at 3-torus. In fact we construct a sequence of such surfaces converging to a planar foliation of the 3-torus. In particular, the area of the surface can be chosen arbitrarily large.
openaire +3 more sources
3D Printing of Ceramic Elements with Q-Surface Geometry for the Fabrication of Protective Barrier
Ceramics, 2023 The work proposes the use of aluminum oxide-based ceramic objects with a TPMS-Q-surface geometry as elements of armor structures. The samples were produced using the SLA-DLP 3D printing method.
Semen V. Diachenko +8 more
doaj +1 more source
Mean survival times of absorbing triply periodic minimal surfaces
Physical Review E, 2009 14 pages, 5 figures, 1 ...
Gevertz, J., Torquato, S.
openaire +3 more sources
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Survival Outcomes in Older Adults with Axial Spondyloarthritis and Concomitant Cancer
Arthritis Care &Research, Accepted Article.Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman +7 more
wiley +1 more source
Materials & DesignTriply periodic minimal surface structures are increasingly used in high-performance engineering applications, but their complex topology and implicit representation hinder integration with conventional CAD/CAE systems. This work proposes a unified NURBS-
Jiayi Li +4 more
doaj +1 more source
A Porous Scaffold Design Method for Bone Tissue Engineering Using Triply Periodic Minimal Surfaces
IEEE Access, 2018 Among the various scaffold design methods, function-based modeling is of great interest due to its accurate controllability for designing pore architectures.
Jianping Shi +5 more
doaj +1 more source