Results 91 to 100 of about 1,682,449 (357)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

A Search for Blues Brothers: X-ray Crystallographic/Spectroscopic Characterization of the Tetraarylbenzidine Cation Radical as a Product of Aging of Solid Magic Blue [PDF]

open access: yes, 2016
Magic blue (MB+˙ SbCl6− salt), i.e. tris-4-bromophenylamminium cation radical, is a routinely employed one-electron oxidant that slowly decomposes in the solid state upon storage to form so called ‘blues brothers’, which often complicate the quantitative
Boddeda, Anitha   +4 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Integrating Shapley Value and Least Core Attribution for Robust Explainable AI in Rent Prediction

open access: yesBuildings
With the widespread application of artificial intelligence in real estate price prediction, model explainability has become a critical factor influencing its acceptability and trustworthiness.
Xinyu Wang, Tris Kee
doaj   +1 more source

Mannich Bases Derived from Melamine, Formaldehyde Alkanoleamines as Novel Corrosion Inhibitors for Mild Steel in Hydrochloric Acid Medium

open access: yesInternational Journal of Electrochemical Science, 2013
The corrosion inhibition of mild steel using two new Mannich bases namely 2,2’,2”((((1,3,5-triazine-2,4,6-triyl)tris(azanediyl)tris(Methylene)tris(azanediyl)triethanol (INH-1) and 2,2’,2”,2”’,2”“((((1,3,5-triazine-2,4,6-triyl)tris(azanediyl)tris ...
Chandrabhan Verma   +2 more
doaj   +1 more source

A Tri-Model Prediction Approach for COVID-19 ICU Bed Occupancy: A Case Study [PDF]

open access: gold, 2023
Nikolaos Stasinos   +7 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Effect of Tris-(hydroxymethyl)-amino methane on microalgae biomass growth in a photobioreactor [PDF]

open access: yes, 2016
© 2016 Elsevier Ltd. One of the buffers namely Tris (Tris-(hydroxymethyl)-amino methane) was used to increase the growth of microalgae by stabilizing the pH value in microalgae cultures.
Bui, XT   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy