Results 121 to 130 of about 1,412,782 (341)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
A Tri-Radiate Tapeworm (Anoplocephala perfoliata Goeze) from the Horse [PDF]
, 1916 F. J. Meggitt
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Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Tri- und Tetrazoliumsalze als Reduktionsindikatoren bei Meerestieren in verschiedenen Entwicklungsstadien [PDF]
, 1949 Hans‐Joachim Bielig, Hans Querner
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Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Thyroxine and Tri-iodothyronine
Medicine, 2003 Abstract The majority of patients who ingest thyroxine accidentally or deliberately remain asymptomatic. Sinus tachycardia, tremor, anxiety, irritability, hyperactivity, fever, sweating and diarrhoea occur commonly after a substantial overdose of thyroxine or tri-iodothyronine.
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Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
On the Connection between Chemical Constitution and Physiological Action:—On the Physiological Action of the Salts of Ammonia, of Tri-niethylamine, and of Tetramethyl-ammonium; of the Salts of Tropia, and of the Ammonium Bases derived from it; and of Tropic, Atropic, and Isatropic Acids and their Salts. With further details on the Physiological Action of the Salts of Methyl-Strychnium and of Ethyl-Strychnium [PDF]
A. Crum Brown, Thomas R. Fraser
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