Results 161 to 170 of about 1,682,449 (357)

High-precision THz Dielectric Spectroscopy of Tris-HCl Buffer [PDF]

open access: yes
Tris-HCl buffer solution is extensively used in biochemistry and molecular biology to maintain a stablepH for biomolecules such as nucleic acids and proteins.
Do, Y   +5 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tris inhibits a GH1 β-glucosidase by a linear mixed inhibition mechanism.

open access: yesPLoS ONE
Here we demonstrate that Tris (2-amino-2-(hydroxymethyl)-1,3-propanediol), largely used as a buffering agent, is a linear mixed inhibitor (Ki =  12 ±  2 mM and α =  3 ±  1) of the GH1 β-glucosidase from the insect Spodoptera frugiperda (Sfβgly).
Rafael S Chagas, Sandro R Marana
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Reactions between Carbon Dioxide and Amino Alcohols. IV. Tris(hydroxymethyl)aminomethane. [PDF]

open access: bronze, 1963
Marianne Grønvald   +4 more
openalex   +1 more source

Palatabilitas Beberapa Hijauan Pakan pada Kelinci [PDF]

open access: yes, 2009
Penelitian ini bertujuan untuk mengetahui palatabilitas beberapa hijauan pakan ternak yang banyak dijumpai sebagai pakan kelinci. Untuk mengetahui palatabilitas hijauan pakan pada kelinci dilakukan 2 (dua)tahapan percobaan, yaitu (1) pilihan pakan bebas (
Akbarillah, T. (Tris)   +1 more
core  

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

A Homologous Series of Cobalt, Rhodium, and Iridium Metalloradicals [PDF]

open access: yes, 2012
We herein present a series of d7 trimethylphosphine complexes of group 9 metals that are chelated by the tripodal tetradentate tris(phosphino)silyl ligand [SiP^(iPr)_3]H ([SiP^(iPr)_3] = (2_(-i)Pr_2PC_6H_4)_3Si^–).
Peters, Jonas C., Takaoka, Ayumi
core   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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