Results 261 to 270 of about 1,412,782 (341)

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Intramolecular sensitization and structure of a Tb³⁺/2-hydroxyquinoline conjugate in the paraoxonase 1 active site.

Dalton Trans
Smerkolj J, Bahun M, Poklar Ulrih N, Bavec A, Pavšič M, Goličnik M.   +5 more
europepmc   +1 more source

Self-Assembly of Alkynylplatinum(II) Complexes for Sialic Acid Detection and Differentiation of Cancer Cells from Normal Cells. [PDF]

J Am Chem Soc
Guo J, Wong EK, Xu GX, Law AS, Chan MH, Lam J, Chen Z, Lo KK, Yam VW.   +8 more
europepmc   +1 more source

Achieving Chemical Recognition, Recycling, and Circularity With Radical Nanostructures

Advanced Functional Materials, EarlyView.
Here, innovative 3D radical nanostructures based on 4,4′‐dicyano‐2,2′‐biphenylene‐fused tetrazolinyl radical, fabricated on interdigitated gold‐SiO2 hybrid surfaces are presented. They retain their magnetic properties, their morphology and size can can tune, selectively remove them from specific substrate regions using distilled water, and return the ...
Arkaprava Das, Ewa Malgorzata Nowik‐Boltyk, Tobias Junghöfer, Elke Nadler, Farzan Gity, Paul K. Hurley, Zhimin Yang, Andrzej Rajca, Francesco Tavanti, Arrigo Calzolari, Maria Benedetta Casu   +10 more
wiley   +1 more source

Stereoselective Biosynthesis of Bichiral Amino Alcohols from Diketone via Difunctionalization. [PDF]

ACS Omega
Wu T, Song W, Wu J, Wen J, Wei W, Liu L.
europepmc   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

OmpA Specifically Modulates the Activity of Enzymes that Reside in the Crowded Bacterial Outer Membrane. [PDF]

J Mol Biol
Machin JM, Ranson NA, Radford SE.
europepmc   +1 more source

Au@h‐BN Core–Shell Nanostructure as Advanced Shell‐Isolated Nanoparticles for In Situ Electrochemical Raman Spectroscopy in Alkaline Environments

Advanced Functional Materials, EarlyView.
This study demonstrates the stability and Raman signal enhancement effects of Au@h‐BN nanoparticles in an alkaline electrolyte on. A comparison between conventional SiO2 and h‐BN shells reveals that the h‐BN core‐shell structure provides superior stability and enhanced Raman intensity over multiple cyclic voltammetry cycles.
Jee Hyeon Kim, Jihyun Ra, Younghee Park, Junyeon Yoon, Eunji Lee, Hyunseob Lim   +5 more
wiley   +1 more source

Real-time capture of σ^N transcription initiation intermediates reveals mechanism of ATPase-driven activation by limited unfolding. [PDF]

Nat Commun
Mueller AU, Molina N, Nixon BT, Darst SA.   +3 more
europepmc   +1 more source

Transforming Cellulose Into Functional Three‐Dimensional Structures

Advanced Functional Materials, EarlyView.
Cellulose is promising for replacing synthetic polymers due to its excellent mechanical properties and low cost. This review highlights the recent advancements in transforming cellulose into functional 3D structures, including liquid gels and porous materials.
Xia Sun, Hao Sun, Penghui Zhu, Yonggang Wu, Anna Palmer, Feng Jiang   +5 more
wiley   +1 more source