Results 21 to 30 of about 1,053,384 (263)

Utilization of Matrix Effect for Enhancing Resolution in Cation Exchange Chromatography

Molecules
In ion chromatography studies, the matrix effect of other inorganic ions present in the sample is a well-known phenomenon. In this work, the behavior of inorganic and organic ions was studied in a system overloaded with ammonium ions.
Boglárka Páll, Róbert Kormány, Krisztián Horváth   +2 more
doaj   +1 more source

The Therapeutic Potential of Dual NMR (NOP/MOP) Agonism in Pain Management

Pain and Therapy
Addressing pain effectively remains a major global challenge for healthcare systems and public health initiatives. While this issue is pervasive worldwide, it is particularly pressing in the United States, where pain management using opioid analgesics ...
Roberto Ciccocioppo, Jeffrey Gudin, Charles E. Argoff, Emanuela Offidani, James Hackworth, David S. Fam, Jim Potenziano   +6 more
doaj   +1 more source

Kualitas Semen Sapi Brahman pada Persentase Tris Kuning Telur yang Berbeda

Jurnal Sain Peternakan Indonesia, 2019
Tujuan dari penelitian ini adalah mengetahui kualitas semen sapi Brahman pada persentase tris kuning telur yang berbeda.  Penelitian ini dilaksanakan di UPTD Balai Inseminasi Buatan (BIB) Sembawa, Kabupaten Banyuasin, Sumsel dan dilaksanakan pada bulan ...
Ririn Novita, Teguh Karyono, Rasminah Rasminah   +2 more
doaj   +1 more source

Effect of Tris and acetic acid on the stability of titania nanoparticles in different alcohols and their electrophoretic deposition process [PDF]

Processing and Application of Ceramics, 2018
Tris (tris(hydroxymethyl)aminomethane) was used as the dispersant to enhance the colloidal stability of titania nanoparticles in different alcohols (methanol, ethanol, isopropanol and butanol). Acetic acid (AA) was also used to increase the ionization of
Morteza Farrokhi-Rad
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Palatabilitas Beberapa Hijauan Pakan pada Kelinci

Jurnal Sain Peternakan Indonesia, 2015
ABSTRAK Penelitian ini bertujuan untuk mengetahui palatabilitas beberapa hijauan pakan ternak yang banyak dijumpai sebagai pakan kelinci. Untuk mengetahui palatabilitas hijauan pakan pada kelinci dilakukan 2 (dua) tahapan percobaan, yaitu (1) pilihan ...
Hidayat Hidayat, Tris Akbarillah
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source