Results 41 to 50 of about 1,412,782 (341)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Efficacy of soy-lecithin for replacing egg yolk in tris extender on quality of frozen buck semen

open access: yesIndian Journal of Animal Sciences, 2019
The present study undetaken to find the efficacy of incorporating soy-lecithin in tris extender for replacing egg yolk, a widely used animal component. Pooled ejaculates (40), 10 from each of four bucks maintained at Goat Research Station, Burnihat were ...
MANOJ KUMAR KALITA   +5 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Effects of avocado seed extract in different trisextenders on sperm and oxidative stress indices of vitrified goat spermatozoa [PDF]

open access: yesJournal of Agricultural Sciences (Belgrade), 2016
Effects of avocado seed extract (ASE) in different tris-extenders on sperm and seminal oxidative stress indices of vitrified spermatozoa of West African Dwarf (WAD) goats during vitrification were assessed.
Olamitibo Daramola James   +8 more
doaj   +1 more source

Uncommon suffix tries

open access: yesRandom Structures & Algorithms, 2013
AbstractCommon assumptions on the source producing the words inserted in a suffix trie with n leaves lead to a height and saturation level. We provide an example of a suffix trie whose height increases faster than a power of n and another one whose saturation level is negligible with respect to . Both are built from VLMC (Variable Length Markov Chain)
Cénac, Peggy   +3 more
openaire   +5 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Adaptive Reuse of Industrial Buildings for Affordable Housing in Hong Kong [PDF]

open access: yesJournal of Design and the Built Environment, 2014
In response to the urban shortage of affordable housing, this paper elaborates on research findings on potential solutions for alleviating the current housing crisis in Hong Kong.
Tris Kee
doaj  

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Insight into glass transition temperature and mechanical properties of PVA/TRIS functionalized graphene oxide composites by molecular dynamics simulation

open access: yesMaterials & Design, 2021
Mechanical properties of polyvinyl alcohol (PVA) are of essential importance to the practical application. Much effort has been done to further improve the properties of PVA by modifiers.
Chengyuan Dong   +4 more
doaj  

Tubuloreticular Inclusions in the Absence of Systemic Lupus Erythematosus and HIV Infection: A Report of Three Pediatric Cases

open access: yesCase Reports in Nephrology and Dialysis, 2017
Tubuloreticular inclusions (TRIs) are subcellular structures located within the cisternae of endoplasmic reticulum. Formation of TRIs has been linked to the exposure of excess interferon (IFN), either from endogenous or exogenous sources.
Ayah Elmaghrabi   +4 more
doaj   +1 more source

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