Results 41 to 50 of about 58,461 (159)

Placental mosaicism and complications of pregnancy

Медицинский совет, 2021
Timely diagnosis of chromosomal aneuploidies plays an important role in determining the proper approach to the management of pregnancy. This article outlines the current ideas on the likelihood of occurrence of obstetric pathology, depending on the ...
A. A. Sivik, N. K. Tetruashvili
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High‐flow nasal cannula oxygen therapy for respiratory management after postoperative re‐intubation/re‐extubation in patients with trisomy 18 and trisomy 13: Two case reports

Clinical Case Reports, 2023
We present two cases of general anesthesia in children with 18, 13 trisomy. One patient had difficulty with intubation and had to be reintubated postoperatively, another developed postoperative acute respiratory distress syndrome.
Hirofumi Hirano, Yoshie Taniguchi, Masato Kato   +2 more
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Evaluation of Maternal Serum sHLA-G Levels for Trisomy 18 Fetuses Screening at Second Trimester

Frontiers in Genetics, 2021
Human leukocyte antigen-G (HLA-G) has been widely acknowledged to play critical roles in fetal-maternal maintenance. However, the significance of using maternal serum sHLA-G to detect prenatal chromosomal abnormality has not been investigated.
Danping Xu, Yiyang Zhu, Lanfang Li, Yingping Xu, Weihua Yan, Meizhen Dai, Linghong Gan   +6 more
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The Impact of Inherited Thrombophilia on First Trimester Combined Aneuploidy Screening Parameters

Acta Medica Bulgarica
Objective. To investigate the impact of thrombophilia on pregnancy-associated plasma protein A (PAPP-A) and human chorionic gonadotropin (hCG) and the nuchal translucency (NT) during the first trimester of the pregnancy.
Kirovakov Z., Hinkova N., Konova E.
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Retrospective analysis of non-invasive prenatal testing: a population study involving 19,835 participants in the Shaoyang area

Frontiers in Genetics
BackgroundThis cohort study aimed to evaluate the clinical efficacy of Non-invasive prenatal testing (NIPT) in detecting fetal chromosomal abnormalities within a pregnant population in the Shaoyang area, and to further investigate the potential ...
Muping Zhou, Hua Zhang, Jun Wen, Na Liu, Zhongchun Wu, Ting Lin, Mengyun Tang, Yan Huang, Ying Xiao, Hui Xie, Xia Ouyang, Xiang Xiao, Liyuan Deng, Ning Chen, Ani Zeng, Jinping Peng   +15 more
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Identifying Differentially Methylated Sites for Methylation-Sensitive qPCR-based NIPT of Trisomies 13 and 18

Advanced Biomedical Research
Background: Trisomies 13 and 18 are severe chromosomal disorders with high neonatal mortality rates. Noninvasive prenatal testing based on next-generation sequencing provides accurate detection of these aneuploidies but remains costly.
Ali Najafi, Erfaneh Dastbaz, Artin Mehrabani, Morteza Rajabi, Ghazal Sedaghat Shayegan, Mohammad Miryounesi, Mohammad H. Modarressi   +6 more
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Correlation of Pregnancy Associated Plasma Protein A and Zinc with Calculated Risk Ratio of Dual Test [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: First trimester screening by dual test is the most preferred method of antenatal screening. The detection rate of foetal aneuploidy using dual test is 95%.
Indranil Ghoshal, Bolar Suryakanth Varashree, Vijetha Shenoy Belle, Krishnananda Prabhu   +3 more
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Cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes in mosaic double trisomy involving trisomy 7 and trisomy 20 (48,XY,+7,+20) at amniocentesis

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: We present mosaic double trisomy involving trisomy 7 and trisomy 20 at amniocentesis in a pregnancy with a favorable outcome. Case report: A 41-year-old woman underwent amniocentesis at 16 weeks of gestation because of advanced maternal age ...
Chih-Ping Chen, Yi-Hui Lin, Schu-Rern Chern, Peih-Shan Wu, Shin-Wen Chen, Fang-Tzu Wu, Meng-Shan Lee, Yun-Yi Chen, Wayseen Wang   +8 more
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DOWN'S SYNDROME A NEW MATERNAL IRAQI RISK

The Iraqi Journal of Medical Sciences, 2016
Background: The occurrence of Down's syndrome is usually associated with advancing maternal age and increased parity. Objectives: This study explores the risk factor associated with the occurrence of Down's syndrome for different age groups.
Mohammed Sh. Tawfik
doaj   +4 more sources

A rare case of NIPT discrepancy caused by the placental mosaicism of three different karyotypes, 47,XXX, 47,XX,+21, and 48,XXX,+21

Molecular Genetics & Genomic Medicine, 2020
Background Placental mosaicism is one of the major reasons for noninvasive prenatal testing (NIPT) discrepancy. Herein, we discovered a rare case of placenta with complex karyotypes that caused false‐positive and false‐negative results in noninvasive ...
Jin Li, Mingshui Xie, Fang Wang, Jianhong Ma, Jiafu Li, Chen Chen, Zhimin Li, Juan Wang, Yuanzhen Zhang, Yirong Li   +9 more
doaj   +1 more source