Results 51 to 60 of about 76,750 (219)

The association between IVF and chromosomal abnormalities compared to spontaneous conception

Journal of Biochemical and Clinical Genetics, 2021
In vitro fertilization (IVF) is a process by which an egg is extracted by needle aspiration and then combined with a sperm so that fertilization can occur outside the body. Genetic defects, such as chromosomal abnormalities, are considered rare among the
Sawsan Alharthi, Lama Alrasheed, Ghada Alrashed, Ghaida Almutairi, Marwan Nashabat, Majid Alfadhel   +5 more
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

The Impact of Inherited Thrombophilia on First Trimester Combined Aneuploidy Screening Parameters

Acta Medica Bulgarica
Objective. To investigate the impact of thrombophilia on pregnancy-associated plasma protein A (PAPP-A) and human chorionic gonadotropin (hCG) and the nuchal translucency (NT) during the first trimester of the pregnancy.
Kirovakov Z., Hinkova N., Konova E.
doaj   +1 more source

Longitudinal AMH trajectories, ovarian reserve recovery, and fertility outcomes after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia: A real‐world cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize anti‐Müllerian hormone (AMH) recovery after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia (GTN) and evaluate the impact of regimen and hysterectomy. Methods This was a retrospective cohort of 68 high‐risk GTN patients treated with EMA/CO (etoposide, methotrexate, actinomycin D ...
Wei Xue, Tianyi Chen, Yuxiao Wu, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan, Yang Xiang, Junjun Yang   +8 more
wiley   +1 more source

DOWN'S SYNDROME A NEW MATERNAL IRAQI RISK

The Iraqi Journal of Medical Sciences, 2016
Background: The occurrence of Down's syndrome is usually associated with advancing maternal age and increased parity. Objectives: This study explores the risk factor associated with the occurrence of Down's syndrome for different age groups.
Mohammed Sh. Tawfik
doaj   +4 more sources

Retrospective analysis of non-invasive prenatal testing: a population study involving 19,835 participants in the Shaoyang area

Frontiers in Genetics
BackgroundThis cohort study aimed to evaluate the clinical efficacy of Non-invasive prenatal testing (NIPT) in detecting fetal chromosomal abnormalities within a pregnant population in the Shaoyang area, and to further investigate the potential ...
Muping Zhou, Hua Zhang, Jun Wen, Na Liu, Zhongchun Wu, Ting Lin, Mengyun Tang, Yan Huang, Ying Xiao, Hui Xie, Xia Ouyang, Xiang Xiao, Liyuan Deng, Ning Chen, Ani Zeng, Jinping Peng   +15 more
doaj   +1 more source

Referral patterns and patient characteristics in pediatric feeding disorder care at a multidisciplinary outpatient clinic

JPGN Reports, EarlyView.
Abstract Objectives Pediatric feeding disorders (PFDs) are increasingly prevalent in the United States. Limited research has examined referral characteristics for outpatient feeding programs. This study analyzes patient referral characteristics based on referral patterns, patient demographics, and treatment interventions. Methods A retrospective cohort
Edward Tannenbaum, Riad Rahhal, Linda Cooper‐Brown, Willow Cover, Adam Vaske, Dina Al‐Zubeidi   +5 more
wiley   +1 more source

Identifying Differentially Methylated Sites for Methylation-Sensitive qPCR-based NIPT of Trisomies 13 and 18

Advanced Biomedical Research
Background: Trisomies 13 and 18 are severe chromosomal disorders with high neonatal mortality rates. Noninvasive prenatal testing based on next-generation sequencing provides accurate detection of these aneuploidies but remains costly.
Ali Najafi, Erfaneh Dastbaz, Artin Mehrabani, Morteza Rajabi, Ghazal Sedaghat Shayegan, Mohammad Miryounesi, Mohammad H. Modarressi   +6 more
doaj   +1 more source

Characterizing Post Tonsillectomy Respiratory Complications in Patients Under Three

The Laryngoscope, EarlyView.
ABSTRACT Objective To characterize the postoperative respiratory complications in children < 3 years old who underwent tonsillectomy. Methods Retrospective chart review of patients < 3 years old at time of tonsillectomy. Demographics, comorbidities, polysomnography results, intraoperative factors, and postoperative respiratory complications ...
Nathan E. Lu, Fendi Obuekwe, Amber D. Shaffer, Marina V. Rushchak, Amanda L. Stapleton   +4 more
wiley   +1 more source

Cytogenetic discrepancy between cultured amniocytes and uncultured amniocytes in mosaic double trisomy involving trisomy 7 and trisomy 20 (48,XY,+7,+20) at amniocentesis

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: We present mosaic double trisomy involving trisomy 7 and trisomy 20 at amniocentesis in a pregnancy with a favorable outcome. Case report: A 41-year-old woman underwent amniocentesis at 16 weeks of gestation because of advanced maternal age ...
Chih-Ping Chen, Yi-Hui Lin, Schu-Rern Chern, Peih-Shan Wu, Shin-Wen Chen, Fang-Tzu Wu, Meng-Shan Lee, Yun-Yi Chen, Wayseen Wang   +8 more
doaj   +1 more source