Results 131 to 140 of about 81,827 (263)

Lymphotoxin is an autocrine growth factor for Epstein-Barr virus-infected B cell lines. [PDF]

, 1993
Because human lymphotoxin (LT) was originally isolated from a lymphoblastoid cell line, we investigated the role of this molecule in three newly established Epstein-Barr virus (EBV)-infected human B cell lines.
Aggarwal, BB, Estrov, Z, Harris, D, Kantarjian, HM, Kurzrock, R, Pathak, S, Pocsik, E, Talpaz, M, Zipf, TF   +8 more
core   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Distribusi Penderita Sindrom Down Berdasarkan Analisis Sitogenetika Di Laboratorium CEBIOR [PDF]

, 2015
Background : Down syndrome is a condition when a person has an extra number of chromosomes 21 in the form of either classical trisomy 21, translocation or mosaic.
Berlinda, Impi, Eka Putra, Farmaditya, Faradz, Sultana M H   +2 more
core   +1 more source

Values of Individuals With Rare Genetic Neurodevelopmental Disorders and Their Family/Caregivers in Healthcare: A Scoping Review to Inform Guideline Development

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Healthcare decision‐making for individuals with rare genetic neurodevelopmental disorders (RGNDs) associated with intellectual disabilities (ID) can be complex due to the intersection of lifelong care needs, limited medical expertise and communication barriers.
Mirthe J. Klein Haneveld, Louise Cox, Petri J. C. M. Embregts, Alistair R. Niemeijer, Martina C. Cornel, Charlotte M. W. Gaasterland, Agnies M. van Eeghen   +6 more
wiley   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Cell‐free DNA test for fetal chromosomal abnormalities in multiple pregnancies

Acta Obstetricia et Gynecologica Scandinavica
Introduction This study aimed to report the screening performance of cell‐free DNA (cfDNA) testing for chromosomal abnormalities in twins, triplets, and vanishing twin pregnancies.
Angel H. W. Kwan, Maria Mar Gil, Shuwen Xue, Yvonne K. Y. Kwok, Doris Lau, Joanna Fung, Andrea Chan, Kwong Wai Choy, Tak Yeung Leung, Liona C. Poon   +9 more
doaj   +1 more source

‘You can't have an ego in this game’: A simulation primed qualitative inquiry of team reflection in paediatrics

Medical Education, EarlyView.
Abstract Introduction Acute care paediatric teams face ambiguous, dynamic patient care situations that demand adaptability to avoid patient harm. Team huddles and adaptation processes have shown promise in mitigating risk and reducing harm. One team process that may occur in huddles is team reflection (TR), defined as a team's capacity to consciously ...
Rustin Meister, Mary E. McBride, Jan B. Schmutz, Mark Adler, Walter Eppich   +4 more
wiley   +1 more source

Characterizing primary transcriptional responses to short term heat shock in Down syndrome.

PLoS ONE
Heat shock stress induces genome-wide changes in transcription regulation, activating a coordinated cellular response to enable survival. We noticed many heat shock genes are up-regulated in blood samples from individuals with trisomy 21.
Joseph F Cardiello, Jessica Westfall, Robin Dowell, Mary Ann Allen   +3 more
doaj   +1 more source

Trisomy 21 [PDF]

, 2020
openaire   +1 more source

The Effectiveness of the Palivizumab Programme in Reducing the Risk of Paediatric Asthma: A Population‐Based Study in Ontario, Canada

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Palivizumab was introduced in Canada in 1998 as a publicly funded programme to reduce respiratory syncytial virus (RSV) disease in high‐risk children. Severe early‐life RSV infections are associated with increased asthma risk. Thus, palivizumab may also indirectly reduce paediatric asthma.
Kimberley A. Foley, Sarah A. Buchan, Dayre McNally, Michelle Dimitris, Sarah Swayze, Jeffrey C. Kwong, Steven Hawken, Sonia Saxena, Dougal Hargreaves, Tiffany Fitzpatrick   +9 more
wiley   +1 more source