Results 141 to 150 of about 81,827 (263)
Analysis of Second Trimester Maternal Quadruple Screening Test for Trisomy 21 and Trisomy 18
Background: The second trimester quadruple screening test for foetal chromosomal abnormalities has been carried out in Slovenia since 2006. Our objective was to analyse the quadruple test results, define sensibility and specificity, the positive and ...
Katja Bricelj +4 more
doaj
ABSTRACT Background Residing in socioeconomically vulnerable areas is known to be associated with increased preterm birth (PTB) risk in the general population. However, the relationship between social vulnerability and PTB remains unexplored among infants with trisomy 21, who experience more than twice the PTB rate of the general population ...
Fatima R. Sheriff +6 more
wiley +1 more source
ABSTRACT Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi +4 more
wiley +1 more source
ABSTRACT Progressive hip displacement is a common problem in children with neurodevelopmental conditions, often leading to painful dislocation and impaired function. Hip reconstruction may be necessary to maintain containment but these reconstructions are major surgery in this vulnerable population.
Renée A. van Stralen +5 more
wiley +1 more source
In Rwanda, Caregivers of children with Down Syndrome face multiple feeding challenges, like development delays and physiological changes of their children, financial limitations, and insufficient partner support, they adapt via increasing frequency meal, time intensive care which promote bonds through love and faith, Additionally They recommend Health ...
Joselyne Rugema +4 more
wiley +1 more source
ABSTRACT Unquestionably, with the increase in life expectancy, dementia has become a significant health issue in Down syndrome (DS). However, in at least a subset of these individuals, cognitive aging can be considered normal, with absence of dementia symptoms even in the presence of Alzheimer's neuropathology.
Livea Carla F. G. Sant'Ana +3 more
wiley +1 more source
Selinexor and Venetoclax Combination in Patients With Relapsed or Refractory Acute Myeloid Leukemia
ABSTRACT Preclinical studies showed a synergistic antileukemia activity with combination of selective XPO1 inhibitor selinexor (SEL) and venetoclax (VEN), with potential to overcome VEN resistance by reducing the anti‐apoptotic protein MCL1. In an investigator‐sponsored, open‐label, phase Ib study (NCT03955783), adult patients with relapsed or ...
Somedeb Ball +11 more
wiley +1 more source
ABSTRACT Objective There is inconsistent data on cancer risk in people with intellectual disability. Our primary objective was to compare the incidence of cancer in people with and without intellectual disability. Methods and Analysis A cohort study using linked population‐based administrative and cancer registry data in New South Wales, Australia 2001–
Julian Trofimovs +4 more
wiley +1 more source
Transoral Robotic Lingual Tonsillectomy for Pediatric Obstructive Sleep Apnea
ABSTRACT Objectives Our objective was to investigate the safety and efficacy of transoral robotic surgery (TORS) lingual tonsillectomy (LT) with and without epiglottopexy and to compare it with non‐robotic approaches for children with obstructive sleep apnea (OSA).
Daniel J. Campbell +4 more
wiley +1 more source

