Results 61 to 70 of about 44,808,645 (302)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
, 2013 (1) Parental strain NCTC 11168, (2) cj0268c knockout mutant (NCTC 11168::cj0268c), (3) complemented knockout mutant (NCTC 11168::cj0268c-comp-cj0268c). The numbers of colonies of the respective fourth dilution plated onto blood agar are shown.
Andreas E. Zautner (217390) +6 more
core +1 more source
Interaction of Preformed Particle Gel and Nonionic Surfactant Triton X-100
, 2013 The adsorption of nonionic surfactant Triton X-100 onto preformed particle gel (PPG) was studied. It is indicated that the adsorption isotherms of Triton X-100 onto PPG can well be fitted by Langmuir model which is used to describe the monolayer molecule
Bai, Baojun +5 more
core +1 more source
Phosphatidylserine decarboxylase from Clostridium butyricum.
Journal of Lipid Research, 1985 Phosphatidylserine decarboxylase activity has been characterized in membrane preparations from Clostridium butyricum ATCC 19398. A particulate fraction was shown to catalyze the formation of phosphatidylethanolamine and plasmenylethanolamine when ...
J N Verma, H Goldfine
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
, 1983 The calcium-transport ATPase of the sarcoplasmic reticulum membranes is irreversibly inactivated by the combined action of Lasolocid and Triton X-100 at concentrations which separately do not interfere with the enzyme's activity.
Lüdi, H., Migala, A., Hasselbach, W.
core +1 more source
Aggregate-based sub-CMC solubilization of hexadecane by surfactants† [PDF]
RSC Advances, 2015 Solubilizaiton of hexadecane by two surfactants, SDBS and Triton X-100, at concentrations near the critical micelle concentration (CMC) and the related aggregation behavior was investigated in this study.
Hua Zhong +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Effect of GL13K peptides on Triton X-100 induced autolysis.
, 2018 E. faecalis OG1RF (A) or the autolysis-deficient strain TX5128 (B) were incubated in PBS with 0.05% Triton X-100 in the absence of peptide (control) or in the presence of 100 mg/L of L-GL13K or D-GL13K (D).
Elliot Larson (4994495) +3 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source