Results 251 to 260 of about 111,207 (280)

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

Advanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang, Tiantian Zhang, Huimin Li, Zidan Li, Shuangshuang Yin, Yiman Liu, Chunze Zhang, Yuling Qiu, Haiyang Yu   +8 more
wiley   +1 more source

Assessment of Strategies for Preserving Swine Viral RNA Targets in Diagnostic Specimens. [PDF]

Microorganisms
Munguía-Ramírez B, Giménez-Lirola L, Zimmerman J.   +2 more
europepmc   +1 more source

Aligned Conductive Magnetic Nanofibers with Directional Magnetic Field Stimulation Promotes Peripheral Nerve Regeneration

Advanced Science, EarlyView.
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan, Wei Yu, Xinggui Wen, Xiangdong Ding, Xiang Li   +4 more
wiley   +1 more source

Liofilização como método de conservação de RNA. [PDF]

, 2011
IBELLI, A. M. G., REGITANO, L. C. de A., SOUZA, J. R. T. de   +2 more
core  

Protective Role of Whey Protein Isolate on MPP⁺-Induced Differentiation of SH-SY5Y Cells by Modulating the Nrf2 Antioxidant Pathway. [PDF]

Molecules
Rungruang P, Sroyraya M, Sansri V.
europepmc   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

Advanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han   +12 more
wiley   +1 more source

U2AF65 mediated circPVT1 promotes NSCLC cell proliferation and inhibits ferroptosis through the miR-338-3p/GPX4 axis. [PDF]

Cell Biol Toxicol
He L, Zhou Z, Wang J, Jiang J, Liu S.
europepmc   +1 more source

PS77: a novel peptide with α-helical structure for targeted anti-inflammatory therapy in biomaterials design. [PDF]

Immunol Res
Lin Z, Zhao H, Lin H, Song L, Tian X, Choo SW.   +5 more
europepmc   +1 more source

Equal performance of HTK-based and UW-based perfusion solutions in sub-normothermic liver machine perfusion. [PDF]

Sci Rep
Leber B, Stimmeder S, Briendl K, Weber J, Rohrhofer L, Aigelsreiter A, Niedrist T, Sucher R, Stiegler P.   +8 more
europepmc   +1 more source

Transparent 3-Layered Bacterial Nanocellulose as a Multicompartment and Biomimetic Scaffold for Co-Culturing Cells. [PDF]

J Funct Biomater
de Oliveira KPV, Yitayew MY, Bastos APA, Mandrik SCN, Porto LM, Tabrizian M.   +5 more
europepmc   +1 more source