Results 251 to 260 of about 116,911 (276)

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

Effects of Sodium Butyrate and Organic Zinc Supplementation on Performance, Mineral Metabolism, and Intestinal Health of Dairy Calves. [PDF]

Animals (Basel)
Martins MM, Gheller LS, Noronha BL, Cassiano GA, Figueiredo MB, Meira CM, Simili FF, Salles MSV, Netto AS.   +8 more
europepmc   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Reversine-Induced Telomere Architecture Remodeling in Chronic Myeloid Leukemia Cell Lines: Insights from TeloView^® Analysis of 3D Nuclear Architecture. [PDF]

Curr Issues Mol Biol
Morato de Oliveira F, Cruvinel ID, Ferreira BMR, Mai S.   +3 more
europepmc   +1 more source

Preliminary toxicity assessment of pharmaceutical solutions with and without ferrate treatment [PDF]

, 2017
Jiang, Jia-Qian, Patibandla, Srinath
core   +1 more source

Isolation, Extraction, and Analysis of Cells After Confined Migration. [PDF]

Curr Protoc
Gao X, Li Y, Lee JWN, Zhou J, Rangaraj V, Sun AR, Young JL, Holle AW.   +7 more
europepmc   +1 more source

Comparative evaluation of 5 combination adjuvants on immunogenicity and efficacy of approved seasonal influenza vaccines. [PDF]

NPJ Vaccines
Hernandez-Davies J, Felgner J, Strahsburger E, Laster J, Jain A, Yates T, Silzel E, Assis R, Nakajima R, Jasinskas A, Yeromin A, Pone EJ, Jan S, de la Maza LM, Liang L, Felgner P, Wagar LE, Gregory AE, Davies DH.   +18 more
europepmc   +1 more source

The Purinergic Receptor P2X5 Modulates Glucose Metabolism and Expression of Thermogenic Genes in Brown Adipose Tissue. [PDF]

Int J Mol Sci
Jaeckstein MY, Miegel L, Behrens J, Stähler T, Diercks BP, Heine M, Koch-Nolte F, Heeren J.   +7 more
europepmc   +1 more source

The effects of graded hypoxia on gene expression related to oxygen sensing and metabolism. [PDF]

Sci Rep
Walker J, Ruby B, Slivka D.
europepmc   +1 more source

Analysis of neuronal activity impairment in iPSC-derived neurons from idiopathic autism patients. [PDF]

iScience
Kern A, Román V, Orbán TI, Pál I, Nagy J, Lévay G, Lendvai B, Némethy Z.   +7 more
europepmc   +1 more source