Results 181 to 190 of about 452,059 (305)

Regular versus Irregular Exercise Differentially Modulates Hippocampal‐Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation

Advanced Science, EarlyView.
Ma et al. report the hippocampal and hepatic acetylcholine (ACh) levels are differently modulated by regular versus irregular exercise, which contributes to coordinate hippocampal astrocyte activity and hepatic FBXL6high neutrophil recruitment. This ACh‐modulated brain‐liver circuit links the effects of exercise on fear memory extinction and liver ...
Pengjiao Ma, Kuan Zhang, Long Yi, Chuanyan Yang, Hedong Lang, Jianbin Sun, Jin Li, Qian Bai, Yuhang He, Shuang‐Shuang Dai, Man‐Tian Mi   +10 more
wiley   +1 more source

Isolation of functional total RNA from Tilia cordata leaves and pollen [PDF]

The conditions required for the isolation of high quality total RNA from European linden (Tilia cordata) leaves and pollen were determined. Pure total RNA was isolated from linden leaves utilizing a Qiagen plant mini kit, while\ud the total RNA isolated ...
Jankov, Ratko M, Ognjenovic, Jana, Tantoush, Ziyad Omar, Vukmirica, Jelena, Ćirković-Veličković, Tanja   +4 more
core   +1 more source

Microfilament‐Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice

Advanced Science, EarlyView.
In this study, we provided new evidence identifying multinucleated cysts as precursors for oocyte differentiation. Within these cysts, organelles migrate and aggregate to form Balbiani body (B‐body) and establish early cellular polarity. Concurrently, excess nuclei are expelled, enabling cyst‐to‐oocyte differentiation. The microfilament‐myosin II plays
Rui Xu, Menghao Pan, Zhi Zheng, Yaju Tang, Yutong Yan, Sihai Lu, Sha Peng, Baohua Ma   +7 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of Some New 1,2,4-Trizoles

Asian Journal of Chemistry, 2017
Rakesh Kumar Jain, Vikash Mishra, Varsha Kashaw   +2 more
openaire   +2 more sources

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
A compartmentalized joint‐on‐chip (JoC) platform is here developed, modelling the interactions between cartilage and synovium in osteoarthritis (OA). Using independent culture and mechanical/biochemical stimulation, the JoC revealed how inflammation and mechanical damage drive mutual tissue changes.
Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta   +6 more
wiley   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS. [PDF]

Int J Mol Sci
Liang L, González Molina LA, Jellema PG, van Faassen M, Otten LTA, Mennega KP, Hof IH, Dijck-Brouwer DAJ, Dolga AM, Rots MG, Niezen-Koning KE.   +10 more
europepmc   +1 more source

Development of modified CTAB and Trizol protocols to isolate high molecular weight (HMW) RNA from polyphenol and polysaccharides rich pigeonpea (Cajanuscajan (L.) Millsp

, 2023
Pawan Mainkar, Deepanshu Jayaswal, Deepesh Kumar, Kuldip Jayaswall, Sandeep Jaiswal, Arvind Nath Singh, Sanjay Kumar, Rekha Kansal   +7 more
openalex   +2 more sources

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

Non-coding RNA profiling in BRAF^V600E-mutant cutaneous melanoma before and after Spry1 depletion. [PDF]

Sci Data
Lamberti J, Memoli D, Montico B, Silvestro F, Guerrieri R, Colizzi F, Weisz A, Salvati A, Fratta E, Nassa G.   +9 more
europepmc   +1 more source