Results 191 to 200 of about 463,109 (314)

Effective Reduction in Nuclear DNA Contamination Allows Sensitive Mitochondrial DNA Methylation Determination by LC-MS/MS. [PDF]

open access: yesInt J Mol Sci
Liang L   +10 more
europepmc   +1 more source

TRIzol for plasmid DNA isolation

open access: yesTechnical Tips Online, 1997
openaire   +1 more source

Extraction of RNA from soybean leaves using the trizol method. v1

open access: yes
The RNA extraction protocol from soybean leaves using the Trizol method presented below is an adaptation of the traditional method, with adjustments to enhance efficiency and minimize contamination and nucleic acid degradation, ensuring an optimized execution.
Ian de Paula Alves Pinto   +1 more
openaire   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma   +11 more
wiley   +1 more source

Non-coding RNA profiling in BRAF<sup>V600E</sup>-mutant cutaneous melanoma before and after Spry1 depletion. [PDF]

open access: yesSci Data
Lamberti J   +9 more
europepmc   +1 more source

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang   +10 more
wiley   +1 more source

Computational Design and Glycoengineering of Interferon‐Lambda for Nasal Prophylaxis Against Respiratory Viruses

open access: yesAdvanced Science, EarlyView.
This study presents an engineered human interferon‐lambda (hIFN‐λ) as an intranasal prophylactic against respiratory viruses. By combining AI‐guided backbone redesign and glycoengineering, the authors developed a thermostable, protease‐resistant, and scalable variant with improved mucosal penetration.
Jeongwon Yun   +12 more
wiley   +1 more source

Development and Optimization of an RNA-Isolating Protocol for Mammalian Spermatozoa. [PDF]

open access: yesInt J Mol Sci
Mounia EO   +7 more
europepmc   +1 more source

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