Results 211 to 220 of about 452,059 (305)

Effective Mixed-Type Tissue Crusher and Simultaneous Isolation of RNA, DNA, and Protein from Solid Tissues Using a TRIzol-Based Method

open access: gold
Kelly Karoline dos Santos   +11 more
openalex   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

open access: yesAdvanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li   +12 more
wiley   +1 more source

Noncoding RNA and Alcohol Use Disorder: A Scoping Review of Current Research and Knowledge Gaps. [PDF]

open access: yesAlcohol Res
Upreti D   +6 more
europepmc   +1 more source

Optimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue [PDF]

open access: green, 2017
Ashley M. Kopec   +4 more
openalex   +1 more source

Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16‐OPTN Axis in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang   +11 more
wiley   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

open access: yesAdvanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou   +8 more
wiley   +1 more source

Protocols for Extraction of miRNA from Extracellular Vesicles of Lyophilized Human Saliva Samples. [PDF]

open access: yesInt J Mol Sci
Quinelato V   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy