Results 271 to 280 of about 241,053 (344)
The RNA‐Puzzles Assessments of RNA‐Only Targets in CASP16
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT RNA‐Puzzles was launched in 2011 as a collaborative effort dedicated to advancing and improving RNA 3D structure prediction. The automatic evaluation protocols for comparisons between prediction and experiment developed within RNA‐Puzzles are applied to the 2024 CASP16 competition.
Eric Westhof +3 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Since CASP13, experimentalists have been encouraged to provide their cryo‐EM data along with the derived atomic models to the CASP organizers to aid assessment. In CASP16, 38 cryo‐EM datasets were provided for assessment, which represented most cryo‐EM targets.
Thomas Mulvaney +2 more
wiley +1 more source
Nucleotide sequence of spinach cytoplasmic serine (IGA) tRNA
, 1989 M A Francis, B. Dudock
openalex +2 more sources
RNA editing system: Balancing altruistic antiviral defense and fitness trade‐offs in fungi
mLife, EarlyView.
Yanfei Du, Daohong Jiang, Huiquan Liu
wiley +1 more source
The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham +3 more
wiley +1 more source
Small, EarlyView.Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
Deciphering epigenetic regulation in postmenopausal osteoporosis: Current and future perspectives
VIEW, EarlyView.In this perspective, the significant roles of microRNAs, long noncoding RNAs and circular RNAs in postmenopausal osteoporosis are thoroughly expounded. The advantages and limitations of typical noncoding RNAs as diagnostic biomarkers and therapeutic targets are summarized and discussed.
Xiumei Tang +10 more
wiley +1 more source
From Yeast to Therapeutics: Modeling Neurodegenerative Diseases in Saccharomyces cerevisiae
Yeast, EarlyView.Yeast plasmids expressing human Aβ‐42, α‐syn, htt, and TDP‐43. Their fate includes an equilibrium between the endocytic pathway and aggregates that potentially disrupt endocytosis, vesicular transport, vacuolar autophagy, and mitochondrial activity. ABSTRACT Here, we review the use of Saccharomyces cerevisiae as a powerful model organism for studying ...
Jose Ribamar Ferreira‐Junior +2 more
wiley +1 more source