Results 311 to 320 of about 404,299 (351)

High‐Quality Genome Assembly of Diplocarpon coronariae Unveils LTR Retrotransposon‐Driven Structural Dynamics in Fungi Evolution

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT Long terminal repeat retrotransposons (LTR‐RTs) are recognised as a significant evolutionary force capable of shaping the structure and function of the genomes in eukaryotes, including animals, plants, and fungi. However, much remains largely unknown about how LTR‐RTs influence the evolution of fungi at the chromosomal level.
Chengyu Gao   +4 more
wiley   +1 more source

OLD amputates the anticodon arm of tRNAs during P2-Lambda interference. [PDF]

open access: yesNucleic Acids Res
Govande AA   +9 more
europepmc   +1 more source

Predicted functional alterations in colonic microbiota metabolism underlie ethanol consumption and preference behavior in mice

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
Using a free‐choice ethanol model, we show that mice switched from a high‐sugar/butter diet to AIN93G standard diet consume and prefer more alcohol than mice maintained on AIN93G. 16S profiling and inferred metabolome revealed reduced amino acid metabolism, increased secondary bile acid pathways, and lower microbiota‐derived SCFAs and selected amino ...
Mírian Velten Mendes   +7 more
wiley   +1 more source

Microenvironment‐Driven Mast Cell Plasticity: Insights From Cytokine‐Activated Gene Signatures in Skin and Respiratory Diseases

open access: yesAllergy, EarlyView.
Primary peripheral blood‐derived human mast cells exposed to IFNγ, IL‐33, IL‐4 + IL‐13, or TGFβ develop distinct transcriptional signatures with unique functional changes including degranulation and cytokine/chemokine release. Machine learning‐defined minimal cytokine‐activated signatures (245 genes) successfully detect cytokine‐primed mast cells in ...
Chiara Tontini   +5 more
wiley   +1 more source

NEAT1 lncRNA overexpression results in short‐term progression and poor treatment outcome in childhood B‐ALL

open access: yesBritish Journal of Haematology, EarlyView.
Childhood acute lymphoblastic leukaemia (chALL) remains the most prevalent malignancy in children and adolescents. Improving risk stratification and providing personalized prognosis and treatment remain major clinical challenges. NEAT1 lncRNA overexpression constitutes a powerful, independent predictor of poor treatment outcomes and disease progression
Marieta Xagorari   +13 more
wiley   +1 more source

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