Results 31 to 40 of about 317,876 (306)
Brünner Beiträge zur Germanistik und Nordistik, 2022 This essay deals with the stage play "Alices Reise in die Schweiz" (Alice's trip to Switzerland) by Lukas Bärfuss, specifically focusing on the main character Gustav.
Jan Trna
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Aminoacyl-tRNA synthetases [PDF]
RNA, 2020 The aminoacyl-tRNA synthetases are an essential and universally distributed family of enzymes that plays a critical role in protein synthesis, pairing tRNAs with their cognate amino acids for decoding mRNAs according to the genetic code. Synthetases help to ensure accurate translation of the genetic code by using both highly accurate cognate substrate ...
Miguel Angel Rubio Gomez, Michael Ibba
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Principles of Palliative and Supportive Care in Pancreatic Cancer: A Review
Biomedicines, 2023 Pancreatic adenocarcinoma (PDAC) is well known for its poor survival time. Clinical symptoms are painless jaundice or abdominal or back pain. Less specific symptoms often appear that make diagnosis difficult, e.g., weight loss, loss of appetite, nausea ...
Robert Mazur, Jan Trna
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Aminoacyl-tRNA synthetase-induced cleavage of tRNA
Nucleic Acids Research, 1992 Aminoacyl-tRNA synthetases interact with their cognate tRNAs in a highly specific fashion. We have examined the phenomenon that upon complex formation E. coli glutaminyl-tRNA synthetase destabilizes tRNA(Gln) causing chain scissions in the presence of Mg2+ ions. The phosphodiester bond cleavage produces 3'-phosphate and 5'-hydroxyl ends.
S, Beresten, M, Jahn, D, Söll
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tRNA-tRNA interactions within cellular ribosomes. [PDF]
Proceedings of the National Academy of Sciences, 1989 We describe an assay that converts the effects of tRNA-tRNA contacts at two particular codons into a quantitative effect on beta-galactosidase level. The assay measures the separate and combined efficiency of suppression at adjacent nonsense codons in vivo using a set of specially created homologous messages.
D, Smith, M, Yarus
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A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex [PDF]
, 2014 Elongator is a conserved, multi-protein complex discovered in Saccharomyces cerevisiae, loss of which confers a range of pleiotropic phenotypes. Elongator in higher eukaryotes is required for normal growth and development and a mutation in the largest ...
Amberg D.C. +5 more
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The kinetic mechanism of bacterial ribosome recycling. [PDF]
, 2017 Bacterial ribosome recycling requires breakdown of the post-termination complex (PoTC), comprising a messenger RNA (mRNA) and an uncharged transfer RNA (tRNA) cognate to the terminal mRNA codon bound to the 70S ribosome.
Chen, Yuanwei +3 more
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Genetic incorporation of D-Lysine into diketoreductase in Escherichia coli cells [PDF]
, 2012 D-Lysine has been genetically introduced into diketoreductase in E. coli cells by utilization of an orthogonal Ph tRNA /Lysyl-tRNA synthetase pair.
Denghuan Yi +4 more
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Drugging tRNA aminoacylation [PDF]
RNA Biology, 2018 Inhibition of tRNA aminoacylation has proven to be an effective antimicrobial strategy, impeding an essential step of protein synthesis. Mupirocin, the well-known selective inhibitor of bacterial isoleucyl-tRNA synthetase, is one of three aminoacylation inhibitors now approved for human or animal use.
Joanne M. Ho +3 more
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Evaluační standardy ve fyzikálním vzdělávání. [PDF]
, 2004 Evaluační standardy fyzikálního vzdělávání jsou klíčovou součástí inovované vzdělávací technologie výuky na základních a středních školách. Článek se zabývá definováním, funkcí a tvorbou těchto standardů.Evaluation standards of physics education are the ...
Trna Josef
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