Results 131 to 140 of about 55,541 (288)

The modification landscape ofP. aeruginosatRNAs

RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria, tRNA modifications are crucial for responding to stress and regulating the expression of virulence factors.
Mariana D. Mandler, Siddhardha S. Maligireddy, Wilfried M. Guiblet, Christina M. Fitzsimmons, Kayla S. McDonald, Delayna L. Warrell, Pedro J. Batista   +6 more
openaire   +2 more sources

Phylogenomics and Biogeography of the Eastern Asian–Eastern North American Disjunct Genus Hylodesmum (Fabaceae)

Biological Diversity, EarlyView.
Integrating data from plastid genomes, nrDNA, and 353 low‐copy nuclear genes, this study establishes a robust phylogenetic framework for Hylodesmum. This framework supports a taxonomic revision recognizing 18 species and reveals a complex pattern of bidirectional EA–ENA dispersal, with mammals as a plausible dispersal agent. ABSTRACT Phylogenomics with
Zhuqiu Song, Gang Yao, Chen Ren, Kaiwen Jiang, Dongxian Xu, Shijin Li   +5 more
wiley   +1 more source

Novel mechanism of post-transcriptional modification of tRNA: insertion of base of Q precursor into tRNA by tRNA transglycosidase reaction

, 1978
Norihiro Okada, Shigeru Noguchi, Hiroshi Kasai, Nobuko Shindo‐Okada, Tadaaki Ohgi, Toshio Goto, Susumu Nishimura   +6 more
openalex   +2 more sources

The 2′-O-methyltransferase responsible for modification of yeast tRNA at position 4 [PDF]

, 2007
Martha L. Wilkinson, Sharon M. Crary, Jane E. Jackman, Elizabeth J. Grayhack, Eric M. Phizicky   +4 more
openalex   +1 more source

Conserved 5-methyluridine tRNA modification modulates ribosome translocation

Proceedings of the National Academy of Sciences
While the centrality of posttranscriptional modifications to RNA biology has long been acknowledged, the function of the vast majority of modified sites remains to be discovered. Illustrative of this, there is not yet a discrete biological role assigned for one of the most highly conserved modifications, 5-methyluridine at position
Joshua D. Jones, Monika K. Franco, Rachel N. Giles, Daniel E. Eyler, Mehmet Tardu, Tyler J. Smith, Laura R. Snyder, Yury S. Polikanov, Robert T. Kennedy, Rachel O. Niederer, Kristin S. Koutmou   +10 more
openaire   +2 more sources

One‐Step and Universal Strategy for the Synthesis of Hypermodified Uracil Phosphoramidites acp3U and cmnm5U

Chemistry – A European Journal, EarlyView.
One‐step, highly efficient, and scalable synthesis of acp3U phosphoramidite is described, as well as a new alternative synthesis of cmnm5U phosphoramidite from a highly versatile intermediate. Latter could be scaled‐up, split, and aliquots turned simultaneously into cmnm5U, nm5U, and mnm5U.
Ewa Mejdr, Lena Heinickel, Thomas Carell, Ivana Mejdr   +3 more
wiley   +1 more source

tRNA and tsRNA: From Heterogeneity to Multifaceted Regulators

Biomolecules
As the most ancient RNA, transfer RNAs (tRNAs) play a more complex role than their constitutive function as amino acid transporters in the protein synthesis process.
Yun Li, Zongyu Yu, Wenlin Jiang, Xinyi Lyu, Ailian Guo, Xiaorui Sun, Yiting Yang, Yunfang Zhang   +7 more
doaj   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

Chemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova, Jieyu Zhao, Chun Kit Kwok   +2 more
wiley   +1 more source

Bacteriophage Infection of the Marine Bacterium Shewanella glacialimarina Induces Dynamic Changes in tRNA Modifications. [PDF]

Microorganisms, 2023
Lampi M, Gregorova P, Qasim MS, Ahlblad NCV, Sarin LP.   +4 more
europepmc   +1 more source

Key RNA-binding domains in the La protein establish tRNA modification levels in Trypanosoma brucei [PDF]

Lankani Gunaratne, Henry Moore, Nicholas Albaum, Ananth Casius, Jeremy C. Henderson, Alan C. Kessler, Eva Hegedűsová, Sneha Kulkarni, Henry C. Arthur, Robert Ross, Zdeněk Paris, Richard J Maraia, Todd M. Lowe, Juan D Alfonzo   +13 more
openalex   +1 more source