Results 251 to 260 of about 55,541 (288)

Molar–Incisor and Generalized Grade C Periodontitis: Distinct Microbiome–Immune Interactions Suggest Divergent Pathogenesis

Journal of Periodontal Research, EarlyView.
Molar–Incisor (PerioC‐MIP) and Generalized (PerioC‐G) Grade C Periodontitis in systemically healthy patients exhibit different microbiological, inflammatory markers, and genomic signatures, as the analysis of subgingival content from North Americans with PerioC‐MIP and Brazilians with PerioC‐G (geographic preference of each respective phenotype ...
Camila S. Stolf, Hélvis E. S. Paz, Murilo C. Paraluppi, Manuela M. V. Miguel, Mauro P. Santamaria, Mabelle F. Monteiro, Deyvid E. Amgarten, Raquel R. A. Franco, Luciana S. Branco‐de‐Almeida, Luciana M. Shaddox, Renato C. V. Casarin   +10 more
wiley   +1 more source

Reviewer #3 (Public review): Loss of the s2U tRNA modification induces antibiotic tolerance and is linked to changes in ribosomal protein expression

Katherine L Cotten, Abigail McShane, Peter C Dedon, Thomas J Begley, Kimberly M Davis   +4 more
openalex   +1 more source

Some of the next articles are maybe not open access.

Related searches:

tRNA modifications and islet function

Diabetes, Obesity and Metabolism, 2018
Efficient and accurate protein translation is essential to producing insulin in pancreatic β‐cells. Transfer RNA (tRNA) is known as the key component of the protein translational machinery. Interestingly, tRNA contains a wide variety of chemical modifications, which are posttranscriptionally catalysed by tRNA modifying enzymes.
Fan‐Yan Wei, Kazuhito Tomizawa
openaire   +2 more sources

Cooperativity between different tRNA modifications and their modification pathways

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2018
Ribonucleotide modifications perform a wide variety of roles in synthesis, turnover and functionality of tRNA molecules. The presence of particular chemical moieties can refine the internal interaction network within a tRNA molecule, influence its thermodynamic stability, contribute novel chemical properties and affect its decoding behavior during mRNA
Mikołaj Sokołowski, Roland Klassen, Alexander Bruch, Raffael Schaffrath, Sebastian Glatt   +4 more
openaire   +2 more sources

Phage-Induced modification of valyl-tRNA synthetase

Journal of Cellular Physiology, 1969
Infection of Escherichia coli: with T4 bacteriophage causes the appearance of a new valyl-tRNA synthetase activity associated with a molecule that, compared to the host enzyme, exhibits a greater resistance to denaturation by heat or urea, a larger molecular volume, a higher rate of sedimentation in sucrose gradients, a greater net positive charge, and
F C, Neidhardt, G L, Marchin, W H, McClain, R F, Boyd, C F, Earhart   +4 more
openaire   +2 more sources

Role of tRNA modification in translational fidelity

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1990
In transfer RNA many different modified nucleosides are found, especially in the anticodon region. In this region, pseudouridine (psi) is found in positions 38, 39 or 40 in a subset of tRNA species, 2-methylthio-6-hydroxyisopentenyladenosine (ms2io6A) is found in position 37 in tRNAs that read codons starting with U and 1-methylguanosine (m1G) is found
T G, Hagervall, J U, Ericson, K B, Esberg, J N, Li, G R, Björk   +4 more
openaire   +2 more sources

Patterns of Base Modification in tRNA

Nature New Biology, 1973
WE have previously demonstrated that the N-hydroxy-succinimide ester of phenoxyacetic acid (HSP) reacts with certain species of rat liver tRNA1. The reactive species were identified by an alteration in their elution pattern on benzoylated DEAE-cellulose chromatography.
openaire   +2 more sources

tRNA Modification: Is Cancer Having a Wobble?

Trends in Cancer, 2017
Translational control of protein synthesis supports tumor development and progression to metastasis. Wobble tRNA modifications are required during translation elongation and sustain proteome homeostasis. Recent work has highlighted the surprising upregulation of the wobble uridine 34 (U34) tRNA cascade in cancer, which underlies the specific ...
Rapino, Francesca, Zhou, Zhaoli, Delaunay, Sylvain, Chariot, Alain, Close, Pierre   +4 more
openaire   +3 more sources

Role of tRNA modifications in human diseases

Trends in Molecular Medicine, 2014
Transfer RNAs (tRNAs) are key for efficient and accurate protein translation. To be fully active, tRNAs need to be heavily modified post-transcriptionally. Growing evidence indicates that tRNA modifications and the enzymes catalyzing such modifications may play important roles in complex human pathologies.
Adrian Gabriel, Torres, Eduard, Batlle, Lluis, Ribas de Pouplana   +2 more
openaire   +2 more sources