Results 71 to 80 of about 5,994 (219)
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
iMetaOmics, EarlyView.The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
Land Degradation &Development, EarlyView.ABSTRACT As the global tourism industry confronts the existential imperatives of the Anthropocene, the remediation of degraded landscapes through regenerative economic models has emerged as a critical frontier in sustainability science. This research presents a rigorous empirical examination of the “restoration–revenue” paradigm, investigating the ...
Xin Sui, Tianchang Chen
wiley +1 more source
Journal of Field Robotics, EarlyView.ABSTRACT As a crucial puzzle piece of deep space exploration, exploring small bodies can provide significant scientific insights and valuable mineral resources. Unlike missions to the Moon and Mars, small‐body missions pose distinct technical challenges, including communication delays, weak gravity, and uncertain environments. This paper reviews a full
Xin Zhang +3 more
wiley +1 more source
Science Education, EarlyView.ABSTRACT This theoretical paper examines why we make claims like “cooking is chemistry,” what these claims mean, and what good or harm they accomplish. We make three interrelated arguments: First, the relationship between scientific and everyday practices is more complicated and less obvious than is often claimed; second, educators and scientists link ...
Noah Weeth Feinstein, Ryan L. Stowe
wiley +1 more source
IP Soft Core Hardware Trojan Detection Method Based on Grayscale Graph Analysis [PDF]
Jisuanji gongchengWith the refinement of the division of labor in chip design, manufacturing, and packaging processes, the use of third-party Intellectual Property(IP) soft cores for secondary development can significantly improve design efficiency and reduce duplication ...
Lin NI, Zihui LIU, Shuai ZHANG, Jiujiang HAN, Ming XIAN
doaj +1 more source
Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine
Small, EarlyView.Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa +18 more
wiley +1 more source
Small Methods, EarlyView.We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci +8 more
wiley +1 more source
A Feature Selection Method for Remote Access Trojan’s Traffic
四川大学学报. 自然科学版, 2021 In view of the existing Trojan detection methods based on network flow’s anomalous behaviors, there are some problems, such as the lack of representativeness of features, the poor detection effect caused by information redundancy.
ZHANG Yu, LIU Xiao-Jie, LI Bei-Bei
doaj
Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms
The Chemical Record, EarlyView.Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo +11 more
wiley +1 more source
Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models
Environmental Toxicology, EarlyView.ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa +9 more
wiley +1 more source