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Prolonged dopamine and serotonin transporter inhibition after exposure to tropanes
Huw M L Davies +2 more
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Complexation of tropane alkaloids by cyclodextrins
Carbohydrate Polymers, 2019Complexes of atropine, homatropine, scopolamine, and ipratropium with cyclodextrins were investigated by NMR and capillary electrophoresis. It has been demonstrated that tropane alkaloids form complexes with β- and γ-cyclodextrins of 1:1 stoichiometry.
Monika Asztemborska +2 more
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Biosynthetic studies on the tropane ring system of the tropane alkaloids from Datura stramonium
Phytochemistry, 2000Isotopic labelling experiments have been carried out in Datura stramonium root cultures with the following isotopically labelled precursors; [2H3]- [2-13C, 2H3]-, [1-13C, 18O2]-acetates, 2H2O, [2H3-methyl]-methionine, [2-13C]-phenyllactate, [3-2H]-tropine and [2'-13C, 3-2H]-littorine.
R, Duran-Patron +3 more
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Analysis of tropane and related alkaloids
Journal of Chromatography A, 2002The current methods for tropane alkaloid chromatographic separation and determination are summarised. The alkaloids included are: the medicinally applied tropic acid esters hyoscyamine and scopolamine and their derivatives, cocaine and derivatives, the metabolites and degradation products of these compounds occurring in plant material, calystegines as ...
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Conformation of Tropane Alkaloids
Nature, 1953IT has become generally accepted that cyclohexane compounds1 and pyranosides2 possess the chair conformation. By analogy we may assume that piperidine and its derivatives also exist in the chair conformation. Starting from this assumption, it is possible to determine the conformation of tropane alkaloids.
AJAY K. BOSE, DILIP K. ROY CHAUDHURI
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2000
Tropane alkaloids comprise a large group of bases occurring predominantly in the family of the Solanaceae. Structurally they are esters of carboxylic acids with tropine (3-hydroxy-8-aza-8-methyl-[3.2.1]-bicyclooctane) and are biosynthetically derived from amino acid and acetate precursors.
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Tropane alkaloids comprise a large group of bases occurring predominantly in the family of the Solanaceae. Structurally they are esters of carboxylic acids with tropine (3-hydroxy-8-aza-8-methyl-[3.2.1]-bicyclooctane) and are biosynthetically derived from amino acid and acetate precursors.
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