Results 21 to 30 of about 3,796 (180)

Endoscopic diagnosis of Whipple disease in a patient without gastrointestinal symptoms: A case report

open access: yesDEN Open, 2022
Whipple's disease is a systemic chronic bacterial infection caused by Tropheryma whipplei, a gram‐positive bacillus. T. whipplei infection in the small intestine often causes malabsorption and is often accompanied by gastrointestinal symptoms such as ...
Yujiro Henmi   +9 more
doaj   +1 more source

Pulmonary parenchymal involvement caused by Tropheryma whipplei

open access: yesOpen Medicine, 2021
We report a 26-year-old man with left chest pain for 4 days. His chest CT showed a cavity in the left upper lung. Tuberculosis was suspected first, but metagenomics next generation sequencing (mNGS) in bronchoalveolar lavage fluid only detected ...
Zhang Wen Mei, Xu Ling
doaj   +1 more source

Molecular detection of Tropheryma whipplei, Cryptosporidium spp., and Giardia lamblia among celiac disease samples

open access: yesJournal of Research in Medical Sciences, 2020
Background: Celiac disease (CD) is one of the most common disorders, resulting from both environmental (gluten) and genetic factors. The clinical features of the Iranian CD are still unknown and there is insufficient information about the atypical ...
Mostafa Sayyadi   +3 more
doaj   +1 more source

A Case of Whipple's Disease Related Infectious Endocarditis

open access: yesРациональная фармакотерапия в кардиологии, 2020
Whipple's disease is caused by Tropheryma whipplei and is known to have protean clinical presentation which could be influenced by patient's immunologic and genetic features.
N. V. Ivanova   +4 more
doaj   +1 more source

Cultivation of \u3cem\u3eTropheryma whipplei\u3c/em\u3e from Cerebrospinal Fluid [PDF]

open access: yes, 2003
Whipple disease (WD) is a systemic disorder caused by the bacterium Tropheryma whipplei. Since the recognition of a bacterial etiology in 1961, many attempts have been made to cultivate this bacterium in vitro.
Fredricks, David N.   +5 more
core   +5 more sources

Valvular Endocarditis and Biventricular Heart Failure in the Setting of Tropheryma whipplei Disease [PDF]

open access: yesTexas Heart Institute Journal
Whipple disease is a rare systemic illness associated with weight loss, diarrhea, and arthralgia. Asymptomatic carriage is common, but the disease can be complicated by cardiac involvement and may result in culture-negative endocarditis.
Defne Gunes Ergi, MD   +5 more
doaj   +1 more source

Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]

open access: yes, 2014
Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K   +8 more
core   +1 more source

Constrictive pleuropericarditis: a dominant clinical manifestation in Whipple’s disease [PDF]

open access: yes, 2014
Background: Whipple’s disease is a rare, multisystemic, chronic infectious disease which classically presents as a wasting illness characterized by polyarthralgia, diarrhea, fever, and lymphadenopathy. Pleuropericardial involvement is a common pathologic
Alan N Baer   +5 more
core   +1 more source

Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 19, Issue 11, Page 5209-5231, November 2023., 2023
Abstract Microbial infections of the brain can lead to dementia, and for many decades microbial infections have been implicated in Alzheimer's disease (AD) pathology. However, a causal role for infection in AD remains contentious, and the lack of standardized detection methodologies has led to inconsistent detection/identification of microbes in AD ...
Richard Lathe   +30 more
wiley   +1 more source

Tropheryma whipplei, the agent of Whipple's disease, affects the early to late phagosome transition and survives in a Rab5- and Rab7-positive compartment.

open access: yesPLoS ONE, 2014
Tropheryma whipplei, the agent of Whipple's disease, inhibits phago-lysosome biogenesis to create a suitable niche for its survival and replication in macrophages. To understand the mechanism by which it subverts phagosome maturation, we used biochemical
Giovanna Mottola   +6 more
doaj   +1 more source

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