Results 51 to 60 of about 3,796 (180)
Whipple's disease was initially described in 1907. Over the next century, the clinical and pathological features of this disorder have been better appreciated. Most often, weight loss, diarrhea, abdominal and joint pain occur. Occasionally, other sites of involvement have been documented, including isolated neurological disease, changes in the eyes and
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Back from the brink of obscurity
A mutation in a transcription factor makes people susceptible to Tropheryma whipplei, the bacterium that causes a rare condition called Whipple's disease.
Donald C Vinh
doaj +1 more source
Tropheryma whipplei endocarditis without gastrointestinal involvement [PDF]
Whipple's disease, caused by the bacterium Tropheryma whipplei, is a rare chronic multi-system illness commonly affecting the gastrointestinal (GI) tract and presenting with a triad of diarrhoea, weight loss and malabsorption. While 20-55% of patients with a diagnosis of Whipple's disease have clinically evident cardiac manifestations, the initial ...
Susannah M, Love +3 more
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Durchfall ist ein häufiges und komplexes Problem mit vielfältigen infektiösen und nicht-infektiösen Ursachen. Eine sorgfältige klinische und epidemiologische Evaluation des Durchfalls ist entscheidend für die weitere Abklärung und Therapie.
Ortega, Natalie, Rampini, Silvana
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Whipple's Disease and “Tropheryma whippelii” [PDF]
SUMMARYWhipple's disease is a rare bacterial infection that may involve any organ system in the body. It occurs primarily in Caucasian males older than 40 years. The gastrointestinal tract is the most frequently involved organ, with manifestations such as abdominal pain, malabsorption syndrome with diarrhea, and weight loss.
F, Dutly, M, Altwegg
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Endocarditis infecciosa por Tropheryma whipplei: un desafío en la actualidad
Resumen: La endocarditis infecciosa es una enfermedad mortal, que a pesar de las mejoras en su manejo sigue estando asociada a gran mortalidad y complicaciones graves.
Carlos Domínguez-Massa +5 more
doaj +1 more source
Uptake of Tropheryma whipplei by Intestinal Epithelia
Background: Tropheryma whipplei (TW) can cause different pathologies, e.g., Whipple’s disease and transient gastroenteritis. The mechanism by which the bacteria pass the intestinal epithelial barrier, and the mechanism of TW-induced gastroenteritis are currently unknown.
Julian Friebel +13 more
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Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal +7 more
wiley +1 more source
Tumoural form of Whipple's disease simulating carcinomatosis
Whipple's disease is a rare disease caused by the actinomycete bacteria Tropheryma whipplei, which cause intestinal infection. The most common symptoms are chronic diarrhoea, weight loss, abdominal pain, arthritis and neurological abnormalities, which ...
Jamille Hemétrio Salles Martins Costa +4 more
doaj +1 more source
MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
A Freitag +59 more
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