Results 151 to 160 of about 60,792 (295)

Understanding pre‐eclampsia and fetal growth restriction at high altitude: A narrative review

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 62-69, July 2026.
Abstract Pre‐eclampsia (PE) and fetal growth restriction (FGR) are among the leading causes of maternal and perinatal morbidity and mortality worldwide. Both conditions are more frequent and severe at high altitudes due to physiological changes in oxygen availability and vascular adaptation.
Víctor S. Rangel, Juliana Malagón Castillo, Juan David Duarte, Mariana Abril Barreto, Alejandra Vivas Ramirez, José Alejandro Daza, Ángela María Ruiz‐Sternberg   +6 more
wiley   +1 more source

Semaglutide Induces Oxidative Stress and Differentially Modulates mTOR-Dependent Growth and Invasion in Human Trophoblast Cell Models: Implications for Placental Function. [PDF]

Curr Issues Mol Biol
Thurmond E, Roeth EJ, Noyes K, Boyer M, Evans E, Bikman BT, Reynolds PR, Arroyo JA.   +7 more
europepmc   +1 more source

Interdisciplinary management of a viable term abdominal ectopic pregnancy

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Introduction Abdominal ectopic pregnancies are rare and associated with increased maternal morbidity and mortality. As the majority are diagnosed early in gestation, there are few reports of management of advanced abdominal ectopic pregnancies. Case A 41‐year‐old gravida 2 para 1 presented with fatigue and a known left ovarian cyst.
Sarena Hayer, Natasha Q. McGlaun, Katerina A. Furman, Michael R. Manuel, Gouri B. Sadananda, Daniel Manzoor, Swati Bhardwaj, Tanu Patel, Sara Dayanim, John A. Ozimek   +9 more
wiley   +1 more source

<i>Porphyromonas gingivalis</i> outer membrane vesicles prevent the induction of tolerogenic dendritic cells by first trimester trophoblast cells. [PDF]

Front Immunol
Lara B, Schafir A, Fretes A, Materazzi L, Merech F, Rios D, Ramhorst R, Pérez Leirós C, Vota D, Gori S, Hauk V.   +10 more
europepmc   +1 more source

The transcriptional regulatory network modulating human trophoblast stem cells to extravillous trophoblast differentiation

During human pregnancy, extravillous trophoblasts play crucial roles in placental invasion into the maternal decidua and spiral artery remodeling.
Muyoung Lee, Albert J. Son, Yu Jin Jang, Jonghwan Kim, Mijeong Kim, Nikita A. Kakkad, Abigail B. Roland, Bum-Kyu Lee, Qingqing Guo   +8 more
core   +1 more source

Validation of a Pregnancy‐Associated Glycoprotein–Based Lateral Flow Assay for Early Pregnancy Detection in Goats

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
The commercial AOFPT developed to detect PAG molecules in bovine serum, was observed to be a rapid, practical, and effective method for early pregnancy diagnosis for to improve reproductive performance and herd management strategies in goats, especially following the post‐mating 28th day .
Mehmet Can Kara, Ayşe Merve Köse
wiley   +1 more source

Understanding Preeclampsia: Integrating Placental Dysfunction, Immune Dysregulation and microRNA-Mediated Epigenetic Regulation. [PDF]

Int J Mol Sci
Procopciuc LM, Caracostea GV, Hangan AC, Lucaciu RL.   +3 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, Volume 16, Issue 6, Page 1102-1114, June 2026.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The role of miRNA in modulating oxidative stress in preeclampsia: current knowledge. [PDF]

RNA Biol
Lin C, Xu Q, Yan J, Cao B, Song Y, Tang C.   +5 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, Volume 16, Issue 6, Page 1166-1180, June 2026.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source