Results 151 to 160 of about 88,307 (280)

A Rare Case of P‐Null Phenotype Identified During Preoperative Screening

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 46‐year‐old woman scheduled for an elective total abdominal hysterectomy was incidentally found to have a rare P‐null (p) phenotype during routine preoperative testing. Although her ABO/Rh type was A positive, the antibody screen demonstrated strong pan‐reactivity with all panel cells, while the autocontrol was negative, indicating an ...
Alireza Abdollahi, Aysan Nozheh, Hassan Sohrabinia, Samaneh Salarvand   +3 more
wiley   +1 more source

Hypoxia regulates epithelial to mesenchymal transition-associated genes in human trophoblast cells by modulating DNA methylation. [PDF]

PLoS One
Choudhury J, Dhole B, Aggarwal K, Singh P, Jala MA, Pandey D, Chaturvedi PK, Gupta S.   +7 more
europepmc   +1 more source

High‐dimensional multiomics reveals perturbations to IL‐6/IL‐6R axis and RUNX3 in CD4+ T cells during third‐trimester pregnancy

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
Abstract Objectives CD4+ T cells play key roles in regulating immune responses during pregnancy; therefore, we aimed to understand the CD4+ T‐cell surface proteome and transcriptome during pregnancy. Methods CD4+ T cells were analysed in blood and decidua from term pregnancies (> 37 weeks) and non‐pregnant blood.
Jennifer R Habel, Thi H O Nguyen, Natasha de Alwis, E Kaitlynn Allen, Shihan Li, Morgan J Skinner, Jennifer A Juno, Stephen J Kent, Katherine Bond, Deborah A Williamson, Martha Lappas, Natalie J Hannan, Susan Walker, Jan Schroeder, Jeremy Chase Crawford, Paul G Thomas, Katherine Kedzierska, Louise C Rowntree   +17 more
wiley   +1 more source

Upregulated lncRNA XIST drives trophoblast dysfunction through targeting miR-545-5p/POU2F1 axis in recurrent spontaneous abortion. [PDF]

Am J Transl Res
Qian Y, Chen Z, Niu H, Xing L, Wang Y, Jiang L.   +5 more
europepmc   +1 more source

New Frontiers in the Pathophysiology of Hypertensive Pregnancy Disorders: A Systematic Review of Molecular Insights into Preeclampsia. [PDF]

Curr Issues Mol Biol
Constantin Dimcea DA, Petca A.
europepmc   +1 more source

Sonographic Predictors and Long‐Term Reproductive Outcomes in Recurrent Cesarean Scar Pregnancy

Journal of Ultrasound in Medicine, Volume 45, Issue 5, Page 1059-1068, May 2026.
Objectives To explore the ultrasound findings, treatment strategies, and reproductive outcomes in patients with recurrent cesarean scar pregnancy (CSP), providing evidence for clinical management. Methods We identified 1371 confirmed CSP from 1517 initially screened cases (2012–2022) through blinded image review. From 159 subsequent live births in this
Jianan Shi, Xiaoping Gong, Hui Wang, Tiantian Sun, Guanjie Wang, Ping Chen, Mingtao Xiong   +6 more
wiley   +1 more source

IL-8-driven neutrophil NETosis triggers endothelial apoptosis and exacerbates preeclampsia. [PDF]

J Transl Med
Li W, Li X, Liu X, Zhang M, Li W, Jiao X, Gao F, Cui B.   +7 more
europepmc   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

The Self-amplifying Inflammatory Cascade in Obstetric Antiphospholipid Syndrome: From Pathophysiology to Placenta-centric Immunotherapeutic Targets. [PDF]

Clin Rev Allergy Immunol
Yan R, Wei Y, Chen L, Zhu S, Dong X.
europepmc   +1 more source

Maternal Chrono‐Nutrition and Placental DNA Methylation: The BiSC Study

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This is the first study to examine how the timing of a mother's meals during pregnancy relates to changes in placental DNA methylation, an epigenetic mark. We found that the timing of the last daily meal was most important. Some epigenetic changes were linked to genes involved in placental function and development, and the long‐term health consequences
Joana Llauradó‐Pont, Sofia Aguilar‐Lacasaña, Marta Cosin‐Tomas, Jordi Julvez, Oren Contreras‐Rodríguez, Manolis Kogevinas, Kyriaki Papantoniou, Elisa Gallo, Barbara N Harding, Martine Vrijheid, Payam Dadvand, Mariona Bustamante, Camille Lassale   +12 more
wiley   +1 more source