Results 1 to 10 of about 74,627 (274)

Chorionic trophoblast cells demonstrate functionally different phenotypes from placental trophoblasts†. [PDF]

Biol Reprod
Abstract Chorionic trophoblast cells are one of the principal components of the fetal membrane and join with the decidua to form a feto–maternal interface. Recent success in isolating chorionic trophoblast cells dealt with two separate questions: (i) the necessity of highly enriched and defined media with inhibitors of oxidative stress ...
Choudhury J, Richardson LS, Urrabaz-Garza R, Jacob J, Kammala AK, Menon R.   +5 more
europepmc   +3 more sources

Mechanism of hsa_circ_0069443 promoting early pregnancy loss through ALKBH5/FN1 axis in trophoblast cells [PDF]

iScience
Summary: Studies have shown that circRNAs play an important regulatory role in trophoblast function and embryonic development. Based on sequencing and functional experiments, we found that hsa_circ_0069443 can regulate the function of trophoblast cells ...
Bai-xue Li, Mei-yao Wu, Zhi-hui Wang, Dong-mei Zhou, Jian-qi Li, Bing-feng Lu, Xiao-ling Lin, Yang Zhao, Xiu-jie Sheng   +8 more
doaj   +2 more sources

Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors [PDF]

, 2013
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely ...
A Brar, A Samalecos, A Stavreus-Evers, AA Brahmbhatt, Ana-Maria Bamberger, Anja Wolf, Annemarie Samalecos, AT Fazleabas, B Cloke, B Gellersen, B Gellersen, BA Lessey, Birgit Gellersen, C Ferretti, C Fischer, C Gaggioli, Charlotte H. E. Weimar, CHE Weimar, CM Boomsma, CP Thomas, D Gentilini, D Gentilini, D Haouzi, DE Clark, EE Sander, ER Norwitz, F Chang, F Llorens, F Lyall, G Gaus, G Teklenburg, G Teklenburg, GE Lash, GE Lash, GJ Burton, H Funayama, H Matsumoto, H Xie, HJ Lim, HJ Yoo, I Ihnatovych, IY Yotova, J Anacker, J Baulida, J Fiedler, JJ Brosens, JJ Brosens, JW Tullai, JX Zhu, K Chobotova, K Kawada, K Red-Horse, K Roepstorff, LA Salamonsen, M Bilban, M Bilban, M Cohen, M Gonzalez, M Knöfler, M Knöfler, M Salker, Maren Schwenke, Martin Knöfler, Meijing Wang, Michelle Kruse, MW Maijenburg, Nick S. Macklon, NJ Hannan, NJ Hannan, P Burke, P Jessmon, P Jessmon, P Kaufmann, Philipp Velicky, R Apps, RE Leach, RE Leach, RE Leach, RJ Petrie, RL Kendall, RN Popovici, S Grewal, S Grewal, SK Mitra, Y Jiang, Y Yamazaki   +85 more
core   +23 more sources

12-Oxoeicosatetraenoic acid, a candidate signal for placenta separation, activates matrix metalloproteinase and induces apoptosis in bovine trophoblast cells [PDF]

Animal Bioscience, 2023
Objective 12-oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid (12-KETE), a metabolite of arachidonic acid, is a strong candidate signal for placenta separation following calf discharge at delivery.
Hachiro Kamada
doaj   +1 more source

(Dis)similarities between the Decidual and Tumor Microenvironment

Biomedicines, 2022
Placenta-specific trophoblast and tumor cells exhibit many common characteristics. Trophoblast cells invade maternal tissues while being tolerated by the maternal immune system.
Jelena Krstic, Alexander Deutsch, Julia Fuchs, Martin Gauster, Tina Gorsek Sparovec, Ursula Hiden, Julian Christopher Krappinger, Gerit Moser, Katrin Pansy, Marta Szmyra, Daniela Gold, Julia Feichtinger, Berthold Huppertz   +12 more
doaj   +1 more source

RBM10 Regulates Embryonic Trophoblast Injury via Endoplasmic Reticulum Stress

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Previous studies shown that RNA binding motif proteins (RBM) participate in regulating various physiological processes such as cell autophagy, proliferation, and apoptosis, and are abnormally highly expressed in placental trophoblast cells ...
Xiao Chen, Juan Du, Liyu Chen, Lanlan Wang, Gang Xin   +4 more
doaj   +1 more source

Kisspeptin regulation of genes involved in cell invasion and angiogenesis in first trimester human trophoblast cells. [PDF]

PLoS ONE, 2014
The precise regulation of extravillous trophoblast invasion of the uterine wall is a key process in successful pregnancies. Kisspeptin (KP) has been shown to inhibit cancer cell metastasis and placental trophoblast cell migration.
Víctor A Francis, Aron B Abera, Mushi Matjila, Robert P Millar, Arieh A Katz   +4 more
doaj   +1 more source

Inhibition of LAMP3 mediates the protective effect of vitamin D against hypoxia/reoxygenation in trophoblast cells

Brazilian Journal of Medical and Biological Research, 2023
Inadequate invasion and excessive apoptosis of trophoblast cells are associated with the development of preeclampsia. Vitamin D deficiency in pregnant women may lead to an increased risk of preeclampsia.
Xiaoyu Tian, Lili Zheng, Jing Ma, Ying Xu, Yulin Zhang, Yalei Pi   +5 more
doaj   +1 more source

Trans-differentiation of trophoblast stem cells: implications in placental biology

Life Science Alliance, 2023
Formation of trophendothelial cells is associated with trophoblast differentiation and is regulated by HES1. Trophoblast differentiation–induced TRAIL secretion directs preferential demise of ECs located in their vicinity, aiding trophoblast vasculogenic
Madhurima Paul, Shreeta Chakraborty, Safirul Islam, Rupasri Ain   +3 more
doaj   +1 more source

BPDE induces human trophoblast cell ferroptosis by up-regulating iron metabolism and promoting GPX4 proteasomal degradation

Ecotoxicology and Environmental Safety, 2021
Human trophoblast cells play important role in embryo-fetal development. However, trophoblast cells are sensitive to environmental carcinogens. Recently, we have discovered that BPDE inhibits trophoblast cell migration, invasion and proliferation, and ...
Peng Tian, Zhongyan Xu, Jiarong Guo, Jingsong Zhao, Rong Wang, Weina Chen, Yang Yang, Wenxin Huang, Chenyang Mi, Huidong Zhang   +9 more
doaj   +1 more source