Results 11 to 20 of about 46,140 (234)
Immunobiology of trophoblast cells [PDF]
Trophoblast cells contribute in all the stages of pregnancy starting from implantation of the embryo to parturition through their unique inherent properties of invasion, proliferation, differentiation and endocrine secretions. Hence, successful outcome of pregnancy depends greatly on the coordinated functioning of the trophoblast cells which is brouth ...
C, Das +4 more
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Here and there a trophoblast, a transcriptional evaluation of trophoblast cell models
Abstract A recent explosion of methods to produce human trophoblasts and stem cells (hTSC) is fuelling a renewed interest in this tissue. The trophoblast is critical to reproduction by facilitating implantation, maternal physiological adaptations to pregnancy and the growth of the fetus through transport of nutrients between the mother and ...
Brian Joseph Cox, Kendra Naismith
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Accumulating evidence has shown that the apoptosis of trophoblast cells plays an important role in the pathogenesis of preeclampsia, and an intricate interplay between DNA methylation and polycomb group (PcG) protein-mediated gene silencing has been ...
Xie Lin +13 more
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Natural killer cells (NK cells) are innate immunity lymphocytes. NK cell differentiation is controlled by the cellular microenvironment and locally produced cytokines, including IL-2, IL-15 and IL-18.
V. A. Mikhailova +7 more
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Background Pre‐eclampsia (PE) is mainly attributed to the inflammation of trophoblast cells in pregnant women, which results in damage to the maternal organs and growth retardation of the fetus.
Fang Zong, Yingzi Zhao
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Establishment of Bovine Trophoblast Stem Cells
Abstract Here we report that a chemical cocktail (LCDM: h L IF, C HIR99021, D iM and M iH) previously used for extended potential pluripotent stem cells enables the de novo ...
Yinjuan Wang +8 more
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Human trophoblast cell apoptosis may induce miscarriage. Trophoblast cells are sensitive to environmental BaP-7,8-dihydrodiol-9,10-epoxide (BPDE). However, how BPDE induces human trophoblast cell apoptosis is still largely elusive.
Xinying Huang +8 more
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During early development in placental mammals, proper trophoblast lineage development is essential for implantation and placentation. Defects in this lineage can cause early pregnancy failures and other pregnancy disorders. However, transcription factors
Bum-Kyu Lee +7 more
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Isolation of Primary Mouse Trophoblast Cells and Trophoblast Invasion Assay [PDF]
The placenta is responsible for the transport of nutrients, gasses and growth factors to the fetus, as well as the elimination of wastes. Thus, defects in placental development have important consequences for the fetus and mother, and are a major cause of embryonic lethality.
Kathleen A, Pennington +2 more
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CXCL12/CXCR4 axis triggers the activation of EGF receptor and ERK signaling pathway in CsA-induced proliferation of human trophoblast cells. [PDF]
INTRODUCTION: Our previous study has demonstrated Cyclosporin A (CsA) promotes the proliferation of human trophoblast cells. Therefore, we further investigate the intracellular signaling pathway involved in the CsA-induced proliferation of human ...
Hong-Bo Zhao +6 more
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