Results 11 to 20 of about 46,140 (234)

Immunobiology of trophoblast cells [PDF]

open access: yesIndian Journal of Clinical Biochemistry, 2000
Trophoblast cells contribute in all the stages of pregnancy starting from implantation of the embryo to parturition through their unique inherent properties of invasion, proliferation, differentiation and endocrine secretions. Hence, successful outcome of pregnancy depends greatly on the coordinated functioning of the trophoblast cells which is brouth ...
C, Das   +4 more
openaire   +2 more sources

Here and there a trophoblast, a transcriptional evaluation of trophoblast cell models

open access: yesCellular and Molecular Life Sciences, 2022
Abstract A recent explosion of methods to produce human trophoblasts and stem cells (hTSC) is fuelling a renewed interest in this tissue. The trophoblast is critical to reproduction by facilitating implantation, maternal physiological adaptations to pregnancy and the growth of the fetus through transport of nutrients between the mother and ...
Brian Joseph Cox, Kendra Naismith
openaire   +2 more sources

Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia

open access: yesActa Biochimica et Biophysica Sinica, 2023
Accumulating evidence has shown that the apoptosis of trophoblast cells plays an important role in the pathogenesis of preeclampsia, and an intricate interplay between DNA methylation and polycomb group (PcG) protein-mediated gene silencing has been ...
Xie Lin   +13 more
doaj   +1 more source

Phenotypic Profile of Peripheral Blood NK Cells under Culturing with Trophoblast Cells and IL-15 and IL-18 Cytokines

open access: yesМедицинская иммунология, 2021
Natural killer cells (NK cells) are innate immunity lymphocytes. NK cell differentiation is controlled by the cellular microenvironment and locally produced cytokines, including IL-2, IL-15 and IL-18.
V. A. Mikhailova   +7 more
doaj   +1 more source

Alkaloid leonurine exerts anti‐inflammatory effects via modulating MST1 expression in trophoblast cells

open access: yesImmunity, Inflammation and Disease, 2021
Background Pre‐eclampsia (PE) is mainly attributed to the inflammation of trophoblast cells in pregnant women, which results in damage to the maternal organs and growth retardation of the fetus.
Fang Zong, Yingzi Zhao
doaj   +1 more source

Establishment of Bovine Trophoblast Stem Cells

open access: yesCell Reports, 2022
Abstract Here we report that a chemical cocktail (LCDM: h L IF, C HIR99021, D iM and M iH) previously used for extended potential pluripotent stem cells enables the de novo ...
Yinjuan Wang   +8 more
openaire   +2 more sources

Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop

open access: yesEcotoxicology and Environmental Safety, 2022
Human trophoblast cell apoptosis may induce miscarriage. Trophoblast cells are sensitive to environmental BaP-7,8-dihydrodiol-9,10-epoxide (BPDE). However, how BPDE induces human trophoblast cell apoptosis is still largely elusive.
Xinying Huang   +8 more
doaj   +1 more source

Fosl1 overexpression directly activates trophoblast-specific gene expression programs in embryonic stem cells

open access: yesStem Cell Research, 2018
During early development in placental mammals, proper trophoblast lineage development is essential for implantation and placentation. Defects in this lineage can cause early pregnancy failures and other pregnancy disorders. However, transcription factors
Bum-Kyu Lee   +7 more
doaj   +1 more source

Isolation of Primary Mouse Trophoblast Cells and Trophoblast Invasion Assay [PDF]

open access: yesJournal of Visualized Experiments, 2012
The placenta is responsible for the transport of nutrients, gasses and growth factors to the fetus, as well as the elimination of wastes. Thus, defects in placental development have important consequences for the fetus and mother, and are a major cause of embryonic lethality.
Kathleen A, Pennington   +2 more
openaire   +2 more sources

CXCL12/CXCR4 axis triggers the activation of EGF receptor and ERK signaling pathway in CsA-induced proliferation of human trophoblast cells. [PDF]

open access: yesPLoS ONE, 2012
INTRODUCTION: Our previous study has demonstrated Cyclosporin A (CsA) promotes the proliferation of human trophoblast cells. Therefore, we further investigate the intracellular signaling pathway involved in the CsA-induced proliferation of human ...
Hong-Bo Zhao   +6 more
doaj   +1 more source

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