Results 41 to 50 of about 74,627 (274)

Long noncoding RNA SNHG12 promotes the proliferation, migration, and invasion of trophoblast cells by regulating the epithelial–mesenchymal transition and cell cycle

Journal of International Medical Research, 2020
Objective The deficient placental blood perfusion caused by the attenuated infiltration of trophoblast cells is a key factor in the occurrence of preeclampsia (PE).
Fenmei Zhou, Yanlan Sun, Zhenjing Chi, Qiong Gao, Hairong Wang   +4 more
doaj   +1 more source

A defective CXCL16/CXCR6 axis increases the risk of pregnancy loss via the abnormal crosstalk between decidual γδ t cells and trophoblasts

Reproductive and Developmental Medicine, 2021
Objective: The maternal–fetal interface undergoes dynamic changes to allow the fetus to grow and develop in the uterus. The interaction between decidual γδ Τ cells and trophoblasts plays a pivotal role during successful pregnancy; however, their ...
Deng-Xuan Fan, Ming-Qing Li, Wen-Jie Zhou, Hong-Lan Huang, Hui-Li Yang, Cong-Jian Xu   +5 more
doaj   +1 more source

Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function. [PDF]

, 2014
STUDY QUESTION Are the concentrations of factors secreted by decidual natural killer (dNK) cells from pregnancies at high risk of poor spiral artery remodelling different to those secreted from pregnancies at low risk?
A. E. Wallace, A. P. Johnstone, Athanassiades, Cartwright, Choy, Desai, Engert, Fraser, Furuya, G. S. Whitley, Hanna, J. E. Cartwright, Karamouzis, Kim, King, King, Koga, Meekins, Melchiorre, Moroianu, Nasu, Pijnenborg, Pijnenborg, Pollheimer, Prefumo, Prefumo, R. Fraser, Rehn, S. Gurung, S. S. Goulwara, Santoni, Treiber-Held, van der Harten, Verma, Wei, Zhou   +35 more
core   +2 more sources

Induction of human trophoblast stem cells

Nature Protocols, 2022
Cell reprogramming has allowed unprecedented access to human development, from virtually any genome. However, reprogramming yields pluripotent stem cells that can differentiate into all cells that form a fetus, but not extraembryonic annexes. Therefore, a cellular model allowing study of placental development from a broad genomic repertoire is lacking.
Castel, Gaël, David, Laurent
openaire   +4 more sources

Decidual natural killer cells and trophoblast cells: cellular, humoral and molecular mechanisms of interaction

Медицинская иммунология, 2022
Natural killer cells (NK cells) represent a group of lymphocytes of innate immunity. In addition to NK cells of peripheral blood, tissue-resident populations are described.
P. V. Grebenkina, V. A. Mikhailova, A. A. Oshkolova, S. O. Vershinina, M. S. Dukhinova, D. O. Bazhenov, S. A. Selkov, D. I. Sokolov   +7 more
doaj   +1 more source

Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]

, 2005
Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV, Baker, PN, Cartwright, JE, Crocker, IP, Dash, PR, Wareing, M, Whitley, GS   +6 more
core   +1 more source

Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape

Nature Communications, 2023
The extravillous trophoblast cell lineage is a key feature of placentation and successful pregnancy. Knowledge of transcriptional regulation driving extravillous trophoblast cell development is limited.
Kaela M. Varberg, Esteban M. Dominguez, Boryana Koseva, Joseph M. Varberg, Ross P. McNally, Ayelen Moreno-Irusta, Emily R. Wesley, Khursheed Iqbal, Warren A. Cheung, Carl Schwendinger-Schreck, Craig Smail, Hiroaki Okae, Takahiro Arima, Michael Lydic, Kristin Holoch, Courtney Marsh, Michael J. Soares, Elin Grundberg   +17 more
doaj   +1 more source

Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans

Topics in Cognitive Science, EarlyView., 2023
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica, Michael Levin, Fernando E. Rosas, Karl Friston   +3 more
wiley   +1 more source

NOSTRIN: A novel modulator of trophoblast giant cell differentiation

Stem Cell Research, 2018
Differentiation-dependent expression of NOSTRIN in murine trophoblast cells prompted investigation on NOSTRIN's function in trophoblast differentiation. We show here that NOSTRIN levels increased in both mouse and rat placenta during gestation.
Shreeta Chakraborty, Rupasri Ain
doaj   +1 more source

A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells. [PDF]

PLoS ONE, 2015
The placenta, a transient organ in human, is essential for pregnancy maintenance and for fetal growth and development. Trophoblast and stromal cells are the main cell types present in human placenta.
Wassim Abou-Kheir, Assaad Eid, Rabih El-Merahbi, Rebecca Assaf, Georges Daoud   +4 more
doaj   +1 more source