Results 31 to 40 of about 51,707 (295)

The trophoblast giant cells of cricetid rodents [PDF]

Frontiers in Cell and Developmental Biology, 2023
Giant cells are a prominent feature of placentation in cricetid rodents. Once thought to be maternal in origin, they are now known to be trophoblast giant cells (TGCs). The large size of cricetid TGCs and their nuclei reflects a high degree of polyploidy. While some TGCs are found at fixed locations, others migrate throughout the placenta and deep into
Favaron, Phelipe O., Carter, Anthony M.
openaire   +3 more sources

Monocarboxylate transporter 8 modulates the viability and invasive capacity of human placental cells and fetoplacental growth in mice [PDF]

, 2013
Monocarboxylate transporter 8 (MCT8) is a well-established thyroid hormone (TH) transporter. In humans, MCT8 mutations result in changes in circulating TH concentrations and X-linked severe global neurodevelopmental delay.
Laurence S Loubière, Visser, Theo, Whitley G.S., Elisavet Vasilopoulou (420760), Loubière Laurence S., Darras, V.M. (Veerle), Loubière L.S., Darras, VM, Kilby, MD, Trajkovic-Arsic, M. (Marija), Christopher J McCabe, Guy S Whitley, Heike Heuer (420762), Heuer, H, Marija Trajkovic-Arsic, Guy S. Whitley (420764), Visser T.J., McCabe, Christopher, Gendie E. Lash (420763), Visser Theo J., Theo J. Visser (280338), Marija Trajkovic-Arsic (155746), Kilby, Mark, Franklyn, J.A. (Jayne), Mark D. Kilby (420766), Loubière, LS, Trajkovic-Arsic, M, Lash G.E., Loubière, L.S. (Laurence), Whitley Guy S., Darras, Veerle, Jayne A Franklyn, Christopher J. McCabe (420765), Loubière, Laurence, Heuer Heike, Darras V.M., Jayne A. Franklyn (236549), Whitley, Guy, Lash, G.E. (Gendie), Franklyn, Jayne, Gendie E Lash, Whitley, GS, Vasilopoulou, E, McCabe, CJ, Franklyn Jayne A., Franklyn J.A., Shiao Y Chan, Visser, TJ, Chan, SY, Veerle M Darras, Chan, Shiao, Elisavet Vasilopoulou, Heuer H., Vasilopoulou, Elisavet, Vasilopoulou Elisavet, Heuer, Heike, Lash Gendie E., Visser, T.J. (Theo), Heike Heuer, Shiao Y. Chan (420767), McCabe, C.J. (Christopher), Lash, GE, Chan S.Y., Vasilopoulou, E. (Elisavet), Kilby, M.D. (Mark), Trajkovic-Arsic M., Veerle M. Darras (104459), Heuer, H. (Heike), Chan, S.Y. (Shiao), Laurence S. Loubière (420761), McCabe Christopher J., Whitley, G.S. (Guy), Mark D Kilby, Darras Veerle M., McCabe C.J., Trajkovic-Arsic, Marija, Kilby Mark D., Franklyn, JA, Trajkovic-Arsic Marija, Chan Shiao Y., Lash, Gendie, Vasilopoulou E., Theo J Visser, Kilby M.D.   +83 more
core   +1 more source

Establishment of trophoblast stem cells under defined culture conditions in mice. [PDF]

PLoS ONE, 2014
The inner cell mass (ICM) and trophoblast cell lineages duet early embryonic development in mammals. After implantation, the ICM forms the embryo proper as well as some extraembryonic tissues, whereas the trophoectoderm (TE) exclusively forms the fetal ...
Yasuhide Ohinata, Tomoyuki Tsukiyama
doaj   +1 more source

A defective CXCL16/CXCR6 axis increases the risk of pregnancy loss via the abnormal crosstalk between decidual γδ t cells and trophoblasts

Reproductive and Developmental Medicine, 2021
Objective: The maternal–fetal interface undergoes dynamic changes to allow the fetus to grow and develop in the uterus. The interaction between decidual γδ Τ cells and trophoblasts plays a pivotal role during successful pregnancy; however, their ...
Deng-Xuan Fan, Ming-Qing Li, Wen-Jie Zhou, Hong-Lan Huang, Hui-Li Yang, Cong-Jian Xu   +5 more
doaj   +1 more source

Function of survivin in trophoblastic cells of the placenta [PDF]

Placenta, 2013
Preeclampsia is one of the leading causes of maternal and perinatal mortality and morbidity worldwide and its pathogenesis is not totally understood. As a member of the chromosomal passenger complex and an inhibitor of apoptosis, survivin is a well-characterized oncoprotein.
Muschol-Steinmetz, Cornelia, Friemel, Alexandra, Kreis, Nina-Naomi, Reinhard, Joscha, Yuan, Juping, Louwen, Frank   +5 more
openaire   +5 more sources

Regulation of major histocompatibility complex class II gene expression in trophoblast cells

Reproductive Biology and Endocrinology, 2004
Trophoblast cells are unique because they are one of the few mammalian cell types that do not express major histocompatibility complex (MHC) class II antigens, either constitutively or after exposure to IFN-γ.
Choi Jason C, Murphy Shawn P, Holtz Renae   +2 more
doaj   +1 more source

Long noncoding RNA SNHG12 promotes the proliferation, migration, and invasion of trophoblast cells by regulating the epithelial–mesenchymal transition and cell cycle

Journal of International Medical Research, 2020
Objective The deficient placental blood perfusion caused by the attenuated infiltration of trophoblast cells is a key factor in the occurrence of preeclampsia (PE).
Fenmei Zhou, Yanlan Sun, Zhenjing Chi, Qiong Gao, Hairong Wang   +4 more
doaj   +1 more source

A role for uric acid and the nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast [PDF]

, 2013
Women with antiphospholipid syndrome (APS) are at risk of recurrent pregnancy loss and obstetrical disorders, such as preeclampsia and intrauterine growth restriction (IUGR).
Vikki M Abrahams, Kavathas, Paula B., Melissa J Mulla, Crina M Boeras, Mulla, Melissa J., Paula B Kavathas, Jan J Brosens, Brosens, Jan J., Boeras, Crina M., Larry W Chamley, Jane E Salmon, Abrahams, Vikki M., Salmon, Jane E., Chamley, Larry W.   +13 more
core   +1 more source

Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]

, 2012
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
Weimar, Charlotte H. E., Gellersen, Birgit, Heijnen Cobi J., Johanna M T de Vreeden-Elbertse, Jan J. Brosens (109247), de Vreeden-Elbertse Johanna M. T., de Vreeden-Elbertse, Johanna M.T., Nick S Macklon, Macklon Nick S., Kavelaars, Annemieke, Charlotte H. E. Weimar (148304), Nick S. Macklon (148320), Jan J Brosens, Weimar Charlotte H. E., Gellersen Birgit, Cobi J. Heijnen (148314), Brosens Jan J., Macklon, Nick S., Weimar, Charlotte H.E., Kavelaars Annemieke, Cobi J Heijnen, Charlotte H E Weimar, Birgit Gellersen (148307), de Vreeden-Elbertse, Johanna M. T., Brosens, Jan J., Heijnen, Cobi J., Annemieke Kavelaars, Annemieke Kavelaars (12570), Birgit Gellersen, Johanna M. T. de Vreeden-Elbertse (148309)   +29 more
core   +1 more source

Padi2/3 Deficiency Alters the Epigenomic Landscape and Causes Premature Differentiation of Mouse Trophoblast Stem Cells

, 2022
Histone citrullination is a relatively poorly studied epigenetic modification that involves the irreversible conversion of arginine residues into citrulline. It is conferred by a small family of enzymes known as protein arginine deiminases (PADIs).
Ballasy, Noura N., Noura N. Ballasy, Caroline Kokorudz, Hemberger, Myriam, Kokorudz, Caroline, Bethany N. Radford, Xiang Zhao, Myriam Hemberger, Bering, Elizabeth A., Zhao, Xiang, Wendy Dean, Dean, Wendy, Radford, Bethany N., Elizabeth A. Bering   +13 more
core   +1 more source