Results 31 to 40 of about 46,140 (234)
NK cells, hypoxia and trophoblast cell differentiation [PDF]
Cell Cycle, 2012 Hemochorial placentation is characterized by extensive remodeling of the maternal vasculature, converting them to flaccid low resistance vessels. This process greatly facilitates exchange of nutrients and gases between the mother and the fetus. Two key modulators that orchestrate these vascular changes have been identified at the maternal fetal ...
Damayanti, Chakraborty +2 more
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A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells. [PDF]
PLoS ONE, 2015 The placenta, a transient organ in human, is essential for pregnancy maintenance and for fetal growth and development. Trophoblast and stromal cells are the main cell types present in human placenta.
Wassim Abou-Kheir +4 more
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Медицинская иммунология, 2022 Natural killer cells (NK cells) represent a group of lymphocytes of innate immunity. In addition to NK cells of peripheral blood, tissue-resident populations are described.
P. V. Grebenkina +7 more
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NOSTRIN: A novel modulator of trophoblast giant cell differentiation
Stem Cell Research, 2018 Differentiation-dependent expression of NOSTRIN in murine trophoblast cells prompted investigation on NOSTRIN's function in trophoblast differentiation. We show here that NOSTRIN levels increased in both mouse and rat placenta during gestation.
Shreeta Chakraborty, Rupasri Ain
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Nature Communications, 2023 The extravillous trophoblast cell lineage is a key feature of placentation and successful pregnancy. Knowledge of transcriptional regulation driving extravillous trophoblast cell development is limited.
Kaela M. Varberg +17 more
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The bovine endometrial epithelial cells promote the differentiation of trophoblast stem-like cells to binucleate trophoblast cells [PDF]
Cytotechnology, 2016 Endometrial epithelial cells (EECs) cultured in vitro are valuable tools for investigating embryo implantation and trophoblast differentiation. In this study, we have established the bovine EECs and trophoblast stem-like (TS) coculture system, and used it to investigate the binucleate cell formation of ungulates.
Xiawei, Li +5 more
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Induction of human trophoblast stem cells
Nature Protocols, 2022 Cell reprogramming has allowed unprecedented access to human development, from virtually any genome. However, reprogramming yields pluripotent stem cells that can differentiate into all cells that form a fetus, but not extraembryonic annexes. Therefore, a cellular model allowing study of placental development from a broad genomic repertoire is lacking.
Castel, Gaël, David, Laurent
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Generation of Trophoblast Stem Cells [PDF]
, 2012 The isolation and culture of both embryonic and extraembryonic stem cells provide an enormous opportunity to study the molecular processes that establish and maintain lineage-specific, monoallelic patterns of gene expression. This chapter describes the isolation an culture of trophectoderm stem cells from mouse blastocyst stage embryos.
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Activities for leptin in bovine trophoblast cells [PDF]
Domestic Animal Endocrinology, 2017 Leptin is involved in various reproductive processes in humans and rodents, including placental development and function. The specific ways that leptin influences placental development and function in cattle are poorly understood. This work was completed to explore how leptin regulates hormone, cytokine and metalloprotease transcript abundance, and ...
C.K. Hughes +3 more
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PPARG directs trophoblast cell fate and establishment of the uterine-placental interface
EMBO ReportsThe expansion and differentiation of trophoblast stem (TS) cells are critical for defining fundamental properties of the placenta. Specialized trophoblast cells called extravillous trophoblast (EVT) cells in human and invasive trophoblast cells in rat ...
Esteban M Dominguez +9 more
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