Isolation of Primary Mouse Trophoblast Cells and Trophoblast Invasion Assay [PDF]
Journal of Visualized Experiments, 2012 The placenta is responsible for the transport of nutrients, gasses and growth factors to the fetus, as well as the elimination of wastes. Thus, defects in placental development have important consequences for the fetus and mother, and are a major cause of embryonic lethality.
Kathleen A, Pennington +2 more
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Revisiting Steroidogenic Pathways in the Human Placenta and Primary Human Trophoblast Cells. [PDF]
, 2021 Steroid hormones play a crucial role in supporting a successful pregnancy and ensuring proper fetal development. The placenta is one of the principal tissues in steroid production and metabolism, expressing a vast range of steroidogenic enzymes ...
Fluck, Christa +15 more
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CXCL12/CXCR4 axis triggers the activation of EGF receptor and ERK signaling pathway in CsA-induced proliferation of human trophoblast cells. [PDF]
PLoS ONE, 2012 INTRODUCTION: Our previous study has demonstrated Cyclosporin A (CsA) promotes the proliferation of human trophoblast cells. Therefore, we further investigate the intracellular signaling pathway involved in the CsA-induced proliferation of human ...
Hong-Bo Zhao +6 more
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Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function. [PDF]
, 2014 STUDY QUESTION Are the concentrations of factors secreted by decidual natural killer (dNK) cells from pregnancies at high risk of poor spiral artery remodelling different to those secreted from pregnancies at low risk?
Whitley, G S +11 more
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Differential migration and activation profile of monocytes after trophoblast interaction. [PDF]
PLoS ONE, 2014 Macrophages at the maternal-placental interface coordinate opposite demands under the control of trophoblast cells such as the response against pathogens on one hand, and apoptotic cell clearance and wound healing with the production of suppressor ...
Esteban Grasso +5 more
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What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast
Stem Cell Reports, 2016 Controversy surrounds reports describing the derivation of human trophoblast cells from placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers that define cells as belonging to the trophoblast lineage.
Cheryl Q.E. Lee +8 more
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Natural Killer Cell Derived Microvesicles Affect the Function of Trophoblast Cells
Membranes, 2023 The interaction of natural killer (NK) and trophoblast cells underlies the formation of immune tolerance in the mother–fetus system and the maintenance of the physiological course of pregnancy.
Dmitry Sokolov +8 more
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Oxidative stress stimulates alpha-tocopherol transfer protein in human trophoblast tumor cells BeWo [PDF]
, 2012 alpha-Tocopherol transfer protein (alpha-TTP) has been identified as the major intracellular transport protein for the antioxidant vitamin E (alpha-Tocopherol).
Etzl, Ronny P. +7 more
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Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]
, 2004 Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Streu, Annett +13 more
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Thermotaxis of human trophoblastic cells
Placenta, 1996 The objective of this study was to determine whether cultured human trophoblasts migrate in response to changes in oxygen tension or temperature. Human trophoblastic cells distributed homogenously within individual wells of standard culture plates were subjected to oxygen and thermal gradients.
A A, Higazi +4 more
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