Identification and Validation of DLD as a Cuproptosis‐Associated Biomarker in Preeclampsia
DLD is identified as a preeclampsia‐associated cuproptosis hub gene by bioinformatics. DLD overexpression inhibits trophoblast proliferation, invasion, and migration, disrupts TCA cycle metabolism, and alters mitochondrial ultrastructure. These findings reveal that DLD may contribute to preeclampsia pathogenesis through cuproptosis.
Shuisen Zheng +4 more
wiley +1 more source
Chronic replication stress-mediated genomic instability disrupts placenta development in mice. [PDF]
Munisha M +3 more
europepmc +1 more source
A diameter‐guided workflow was established to define the appropriate trophectoderm (TE) biopsy area window for bovine blastocysts, with the aim of balancing embryo viability and genotyping reliability. After TE biopsy, sampled cells were subjected to DNA amplification and genomic evaluation, while the corresponding biopsied embryos were transferred to ...
Jingyu Zhang +12 more
wiley +1 more source
Something Old, Something New, Something Borrowed… About the Placenta. [PDF]
Milova N +4 more
europepmc +1 more source
Tim1 Deficiency Mediates Gestational Hyperglycemia-Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction. [PDF]
She J +14 more
europepmc +1 more source
Caffeine Exposure Modulates Trophoblast Differentiation and Estradiol Synthesis. [PDF]
Keum J, Lee J, Ryu KY, Roh J.
europepmc +1 more source
From hPSCs to MSCs: differentiation strategies, pathways, and the emergence of common regulatory networks. [PDF]
Liang S +4 more
europepmc +1 more source
In Vitro 3D Model of Human Endometrial Stromal and Trophoblast Cells: Techniques for an Optimized Formation and Cryopreservation of Spheroids. [PDF]
Muthuraj K +5 more
europepmc +1 more source
Endothelial microparticles in high glucose environment: molecular pathways of GDM-associated placental dysfunction and coenzyme Q10-based targeted therapy. [PDF]
Li S +11 more
europepmc +1 more source

