Results 251 to 260 of about 87,349 (342)

Protein Kinase C Regulates Meiosis in Mammalian Oocytes

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
Protein kinase C (PKC) participates in the regulation of mammalian oocyte meiosis. PKC is involved in meiosis resumption in prophase I and in the stabilization of meiosis I and meiosis II spindles. PKC stimulates the maturation‐promoting factor during fertilization and stabilizes the mitotic spindle during early embryo development. ABSTRACT The protein
Jaroslav Kalous   +2 more
wiley   +1 more source

License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
Origin licensing constitutes the first step in initiating eukaryotic genome replication. Licensed origins are marked by an MCM double hexamer complex. This article reviews the molecular mechanisms of MCM double hexamer loading in yeast and higher eukaryotes, based on insights gained from biochemical reconstitution and structural analyses.
Victoria Frisbie, Franziska Bleichert
wiley   +1 more source

Lithium exposure causes ferroptosis to induce unexplained miscarriage through non-canonical MBOAT1 pathway. [PDF]

open access: yesNat Commun
Yi S   +14 more
europepmc   +1 more source

Comprehensive Mapping of Functional Enhancers in Chinese Hamster Ovary Cells

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 1, Page 196-211, January 2026.
In this study, the authors identified regions with enhancer activity in the CHO cell genome using genome‐wide and targeted STARR‐seq. The analysis revealed thousands of newly identified enhancer sequences, where some of the most active sequences could drive transgene expression at levels similar to or higher than strong viral enhancers.
María Santos   +9 more
wiley   +1 more source

Vulnerability of primitive human placental trophoblast to Zika virus

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
M. Sheridan   +13 more
semanticscholar   +1 more source

Strongyloides Antigens Alter Cytokines Responses in Toxoplasma gondii‐Infected BeWo Trophoblast Cells

open access: yesCell Biology International, Volume 50, Issue 1, January 2026.
ABSTRACT The importance of co‐infections is not yet completely understood, and the impact and direction of their effects vary considerably. This study aimed to evaluate the role of total saline extract (TS) and excretory/secretory (ES) products of Strongyloides venezuelensis filarioid larvae on a maternal‐interface cell model during Toxoplasma gondii ...
Fabíola Teixeira Alves   +8 more
wiley   +1 more source

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