Results 261 to 270 of about 87,349 (342)

Ovarian Ectopic Pregnancy at 41‐Week Gestation Age: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Ultrasound demonstrates an empty uterus with the fetal head outside the cavity (A). CT confirms an extra‐uterine fetus originating from the left adnexa (B). ABSTRACT Ovarian ectopic pregnancy is an exceptionally rare entity, typically diagnosed in the first trimester following rupture. Progression to term is extraordinarily uncommon and associated with
Yusuph Mwidibo   +7 more
wiley   +1 more source

UGT1A1 and Sacituzumab Govitecan Toxicity: A Systematic Review and Meta‐Analysis

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 63-73, January 2026.
Sacituzumab govitecan (SG), a humanized antibody‐drug conjugate, enables intra‐tumor delivery of SN‐38, the active metabolite of irinotecan, with the aim of increasing efficacy. SN‐38 is predominantly inactivated by the polymorphically expressed uridine diphosphate glucuronosyltransferase 1A1 (UGT1AA) where reduced activity can lead to toxicity.
Cinzia Dello Russo   +4 more
wiley   +1 more source

ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia. [PDF]

open access: yesGenome Biol
Anwar R   +18 more
europepmc   +1 more source

Feedback regulation between histone H3 lysine 18 lactylation and TROP2‐mediated glycolysis drives metastatic progression of colorectal cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
TROP2 is upregulated in CRC metastasis and promotes lactate overproduction via YBX1‐HIF‐1α signalling. TROP2 signalling induces H3K18la at metastasis genes promoters in CRC and promotes their expression. AccLactate sustains TROP2 expression in CRC cells via H3K18la Acriflavine suppresses TROP2‐driven CRLM by targeting the H3K18la/TROP2 feedback loop ...
Weifeng Wang   +17 more
wiley   +1 more source

Pattern of Detections Across Multiple Environmental Messenger RNAs (e‐mRNAs) in Stressor‐Exposed Zebrafish (Danio rerio)

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
We evaluated e‐mRNAs of known molecular targets of perfluorooctanesulfonic acid (PFOS) toxicity in zebrafish in a controlled laboratory experiment. The detection patterns of e‐mRNAs in our study imply that diminishing detection of these traces over time is a strong indicator of target organism presence (or very recent presence), providing a narrower ...
Denise L. Lindsay   +4 more
wiley   +1 more source

Immune Cells in Preeclampsia. [PDF]

open access: yesInt J Mol Sci
Campbell N   +5 more
europepmc   +1 more source

Developmental Impact of Maternal Immune Activation on the Fetal Immune System and Lung

open access: yesEuropean Journal of Immunology, Volume 56, Issue 1, January 2026.
Maternal immune activation triggers elevated cytokines (IL‐6 and IL‐17A), disrupting fetal immune system development. This not only alters hematopoietic stem cell balance but also leads to ILC2 hyperactivation in the lung, which could potentially affect susceptibility to allergic diseases in the offspring.
Walaa Jradi   +2 more
wiley   +1 more source

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