MicroRNA-22 (miR-22) Regulates Trophoblast Cell Invasion via the Specificity Protein 1 (Sp1)/Cystathionine β-Synthase (CBS)/Matrix Metalloproteinases 2 and 9 (MMP-2 and MMP-9) Pathway: Implications for the Pathogenesis of Preeclampsia. [PDF]
Arora P +5 more
europepmc +1 more source
MON-152 Regulation of Angiogenic Biomarkers of Pre-eclampsia in a Placental Trophoblast Model [PDF]
Hannah M Hooker, Dimitris Grammatopoulos
openalex +1 more source
Neuropilin-1 expression modulates infection susceptibility to murine cytomegalovirus at the materno-fetal interface. [PDF]
Fonseca Brito L +8 more
europepmc +1 more source
Abstract Mid‐trimester pregnancy loss (MTL), defined as a pregnancy loss occurring between 14 + 0 and 21 + 6 weeks of gestation, causes significant physical and emotional distress to women and presents clinical challenges to healthcare professionals. It is acknowledged that in low‐resource settings, this guideline might be applicable to births up to 28
Caroline E. Fox +46 more
wiley +1 more source
Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps
ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira +10 more
wiley +1 more source
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion. [PDF]
Yan S, Wang X, Wu Q, Ding J, Qiu H.
europepmc +1 more source
A Rational Approach to Pharmacotherapy in Pregnancy
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen +2 more
wiley +1 more source
The multifactorial role of HDAC9 at the maternal-fetal interface in the pathogenesis of preeclampsia. [PDF]
Opichka MA, McIntosh JJ, Grobe JL.
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) are key mediators of maternal–foetal communication, regulating placental function and foetal development through the transfer of bioactive molecules. Although placental EVs play a crucial role in placental function during pregnancy, their contribution to foetal development, notably foetal brain, remains poorly ...
Charlène Martin +12 more
wiley +1 more source

