Ras p21 protein activator 1 regulates trophoblast function and its association with preeclampsia through the Ras/mitogen-activated protein kinase pathway. [PDF]
Ding Z, Lu Y, Deng Q, Hua K, Shen X.
europepmc +1 more source
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca +2 more
wiley +1 more source
TET1 modulates trophoblast function by regulation of ODC1 in preeclampsia. [PDF]
Fan C +7 more
europepmc +1 more source
Patient and Family Demographics in the Momcology Pediatric Cancer Patient Advocacy Organization
ABSTRACT Background Momcology is a US‐based patient advocacy organization that provides support for families of children with cancer. This study describes Momcology for researchers by detailing the demographic, clinical, and socioeconomic (socioeconomic status [SES]) data within its registry and comparing it to the National Surveillance, Epidemiology ...
Ryan Salama +6 more
wiley +1 more source
METTL3 safeguards cell identity and epigenome of human trophoblast stem cells. [PDF]
Fu H +20 more
europepmc +1 more source
Placental chorangiomas: Diagnostic challenges and contemporary approaches to fetal care
Abstract Placental chorangiomas are the most common benign tumors of the placenta. Although most are small and asymptomatic lesions, giant chorangiomas are associated with an increased risk of adverse maternal and fetal outcomes. Therefore, in those affected by giant placental chorangioma, early diagnosis and intensive fetal monitoring are indicated to
Tiffany E. Deihl +6 more
wiley +1 more source
Normalization of trophoblast mTOR signaling rescues impaired function in primary human trophoblast cells isolated from pregnancies complicated by fetal growth restriction. [PDF]
Francis EC +6 more
europepmc +1 more source
Abstract Background Preterm birth remains a leading cause of neonatal morbidity and mortality, yet clinicians possess limited tools to identify at‐risk pregnancies and implement effective interventions. This study evaluated whether knowledge of a mid‐second‐trimester maternal blood biomarker test result, combined with an intervention bundle for those ...
Brian K. Iriye +17 more
wiley +1 more source
Evaluation of optimal trophoblastic models to mimic uterine vessel remodeling in human pregnancy†. [PDF]
Li W +7 more
europepmc +1 more source
ABSTRACT Purpose To study incidence, clinical risk factors, and pregnancy outcomes of trophectoderm‐ and inner cell mass–poor‐quality blastocysts in single blastocyst transfer cycles. Design A retrospective cohort study included patients who underwent their first single blastocyst transfer cycle.
Longbin Chen +6 more
wiley +1 more source

