Results 321 to 330 of about 109,495 (390)

Human Trophoblast Cells Are Permissive to the Complete Replicative Cycle of Human Cytomegalovirus

, 1998
Gabriele Halwachs‐Baumann, M. Wilders‐Truschnig, Gernot Desoyé, Tom Hahn, Ludwig Kiesel, Karin Klingel, Peter Rieger, Gerhard Jahn, Christian Sinzger   +8 more
openalex   +1 more source

Mechanism of microRNA‐152 Regulating Decidual Natural Killer Cell Viability and Affecting Trophoblast Cell Invasiveness via the HLA‐G/KIR2DL4 Axis

The Kaohsiung Journal of Medical Sciences, Volume 41, Issue 5, May 2025.
ABSTRACT Trophoblast cells are specialized placental epithelial cells essential for pregnancy maintenance. miR‐152 is implicated in trophoblast cell regulation and pregnancy failure. This study explores the role of miR‐152 in decidual natural killer (dNK) cell viability and trophoblast cell invasion.
Yang Yang, Sai Liu, Xiao‐Ming Zhu, You‐Yi Chen, Jing Zhao, Yu‐Fei Yuan, Yuan Ma   +6 more
wiley   +1 more source

Cystatin 6 (CST6) and Legumain (LGMN) are potential mediators in the pathogenesis of preeclampsia. [PDF]

Sci Rep
Botha SM, Bartho LA, Hartmann S, Cannon P, Nguyen A, Nguyen TV, Pritchard N, Dechend R, Nonn O, Tong S, Kaitu'u-Lino TJ.   +10 more
europepmc   +1 more source

Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
ABSTRACT Dysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and metabolic abnormalities.
Yao Shen, Nairui Fan, Shu‐xia Ma, Xin Cheng, Xuesong Yang, Guang Wang   +5 more
wiley   +1 more source

Extracellular Vesicles Alter Trophoblast Function in Pregnancies Complicated by COVID-19. [PDF]

J Extracell Vesicles
Golden TN, Mani S, Linn RL, Leite R, Trigg NA, Wilson A, Anton L, Mainigi M, Conine CC, Kaufman BA, Strauss JF, Parry S, Simmons RA.   +12 more
europepmc   +1 more source

Organoid‐Guided Precision Medicine: From Bench to Bedside

MedComm, Volume 6, Issue 5, May 2025.
This review focuses on the structural and characterization aspects of organoids derived from original cells and scaffold materials. It also examines the construction methodologies, the incorporation of cytokines, and the practical applications in precision medicine.
Boqiang Tao, Xiaolan Li, Ming Hao, Tian Tian, Yuyang Li, Xiang Li, Chun Yang, Qirong Li, Qiang Feng, Hengzong Zhou, Yicheng Zhao, Dongxu Wang, Weiwei Liu   +12 more
wiley   +1 more source

Microfluidic device successfully replaces traditional models of pregnancy associated drug pharmacokinetic studies

Pregnancy, Volume 1, Issue 3, May 2025.
Abstract Introduction Pregnant and lactating people remain therapeutic orphans as they are often excluded from clinical trials, remaining one of the most therapeutically vulnerable. Current models are not suited to determine pharmacokinetics and dynamics.
Ana Collins‐Smith, Pavani Gonnabathula, Miao Li, Sovik Paul, Pilar Flores‐Espinosa, Lauren S. Richardson, Xiaoming Wang, Ramkumar Menon, Ananth Kumar Kammala   +8 more
wiley   +1 more source

Increased Trophoblast Cell Ferroptosis via HMGB1/ACSL4 Pathway Is Associated with Spontaneous Abortion. [PDF]

Reprod Sci
Dong Y, Li Y, Tang W, Chen Q, Kong C.
europepmc   +1 more source

Enhancing the utility of placental pathology reports for clinical use

Pregnancy, Volume 1, Issue 3, May 2025.
Abstract Obstetric training programs typically offer limited formal education on placental pathology; yet, in practice, obstetric providers are expected to incorporate placental pathology findings into the overall evaluation of obstetric complications.
Janelle Santos, Linda M. Szymanski, Regan N. Theiler, Andrew P. Norgan, Elizabeth Ann L. Enninga, Molly Mcduffie, Lainee A. Bulawa‐Regner, E. Heidi Cheek‐Norgan, Julie A. Lamppa, Myra Wick   +9 more
wiley   +1 more source

The Dysregulation of microRNA-30b Directly Regulates Cystathionine Gamma-Lyase and Exhibits Poor Invasion Activity in Preeclampsia. [PDF]

Cureus
Saxena S, John BA, Verma N, Mishra M.
europepmc   +1 more source