Results 101 to 110 of about 92,904 (199)

The Role of Noncoding RNA in MGMT‐Positive Glioblastoma: A Narrative Review

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Glioblastoma (GBM) is the most aggressive primary malignant tumor of the central nervous system and is characterized by rapid progression, frequent recurrence, and poor survival outcomes. The current standard of care, comprising maximal safe surgical resection followed by radiotherapy with concomitant and adjuvant temozolomide (TMZ), has ...
Junfeng Zhao, Jiaxuan Chen, Yingrui Bai, Ying Li, Yiming Han, Chuankun Han, Yintao Li   +6 more
wiley   +1 more source

Actinomycin Analogs From Streptomyces polyantibioticus S4D258: Structural Elucidation and Antiproliferative Activity Against Triple‐Negative Breast Cancer

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Fifteen new actinomycin analogs, named actinomycins H1–H15, are identified from S. polyantibioticus S4D258. Actinomycins H7–H15 are truncated actinomycin analogs. Actinomycins H1–H6 and H9 exhibit significant antiproliferative activities against both MDA‐MB‐231 and 4T1 TNBC cells.
He Pang, Xiao‐Min Huang, Usama Ramadan Abdelmohsen, Li Shen, Jun Wu   +4 more
wiley   +1 more source

Review of potential doppler ultrasonographic findings in patients with confirmed gestational trophoblastic neoplasms [PDF]

Vojnosanitetski Pregled, 2006
Nikolić Branka, Lazić Jelena
doaj   +1 more source

Head-to-head comparison of [¹⁸F]-fluorodeoxyglucose and [¹⁸F]-fluorocholine positron emission tomography/computed tomography in three patients with rare gestational trophoblastic neoplasms: A case series. [PDF]

World J Nucl Med, 2020
Thientunyakit T, Thongpraparn T, Siriprapa T, Gelovani JG.   +3 more
europepmc   +1 more source

Insights Into the Role of Platelet Factor 4 in Neurodegenerative Diseases

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This review summarizes potential functions of platelet factor 4 (PF4) in neurodegenerative diseases (NDs) and discusses its promise as both a biomarker and a therapeutic target. Further elucidation of PF4 signaling pathways may provide new insights into disease mechanisms and uncover novel opportunities for targeted interventions in NDs.
Qi Tian, Yanji Tong, Fang Yu, Xiaoming Hu   +3 more
wiley   +1 more source

Rare neoplasms

, 2015
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
CIARAVINO, VALENTINA, MALAGO', Roberto, Capelli, Paola, DE ROBERTIS LOMBARDI, Riccardo, PEDICA, Federica, POZZI MUCELLI, Roberto   +5 more
core  

Hepatic HIF2α Modulates Extra‐Hepatic Disease‐Associated Phenotypes During Metabolic Dysfunction‐Associated Steatotic Liver Disease

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
High fat, high fructose, high cholesterol “GAN” diet feeding in mice induces MASLD, cardiac dysfunction, loss of lean mass, and hyperinsulinaemia. Hepatocyte‐specific deletion of HIF2α also causes cardiac dysfunction and loss of lean mass but prevents GAN induced hyperinsulinaemia and cardiac sympathetic dominance without preventing MASLD.
Lorenz M. W. Holzner, Rosa M. Korpershoek, Youguo Niu, Anna Cochrane, Paula M. Darwin, Julia Babuta, Areesha Nazeer, Cecilia Castro, Alice P. Sowton, Alice E. Knapton, Benjamin D. Thackray, Julian L. Griffin, Zoe Hall, Dino A. Giussani, Rob C. I. Wüst, Andrew J. Murray   +15 more
wiley   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Travis, W., Beuschlein, Felix, Karl, M., Chrousos, G. P., Abdelhamid, S., Allolio, B., Jaursch-Hancke, C., Reincke, Martin   +7 more
core   +1 more source

Multi‐omics integration driving precision medicine in non‐small cell lung cancer: From molecular mechanisms to clinical translation

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review pivots from a conventional technology catalogue to a clinical‐problem‐oriented framework for non‐small cell lung cancer. By integrating spatial multi‐omics, metabolomics, and advanced artificial intelligence (e.g. Multi‐Omics Factor Analysis and Least Absolute Shrinkage and Selection Operator), we decode lipid metabolic reprogramming ...
Yuang Gao, Liyan Lin, Hongrui Zhou, Muchen Li, Yunye Mao, Xiangwei Ge, Yangyang Jia, Yupu Li, Shu Sheng, JinZhao Zhai, Boyu Qin, Jinliang Wang   +11 more
wiley   +1 more source

Overexpression of NANOG in gestational trophoblastic diseases: Effect on apoptosis, cell invasion, and clinical outcome

, 2008
Gestational trophoblastic disease includes choriocarcinoma, a frankly malignant tumor, and hydatidiform mole (HM), which often leads to the development of persistent gestational trophoblastic neoplasia and requires chemotherapy.
Wong, ESY, Hoi, YC, Chan, KYK, Ngan, HYS, Siu, MKY, Cheung, ANY   +5 more
core   +1 more source