Results 101 to 110 of about 8,240 (228)
Abstract We present a brief review of epithelioid trophoblastic tumor, a rare trophoblastic neoplasm derived from chorionic-type intermediate trophoblastic cells that typically presents in reproductive-age women between 1 and 18 years following a previous gestation.
Kimberly H, Allison +2 more
openaire +2 more sources
SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source
Evaluation of Treatment Outcomes of High‐Risk Gestational Trophoblastic Neoplasms (GTNs)
This study was performed to assess the efficacy, safety, and prognostic factors of treatment protocols in patients with high‐risk gestational trophoblastic neoplasia (GTN).
Ayberk Çakır +3 more
doaj +1 more source
Possible risk for gestational trophoblastic neoplasm in perimenopause and menopause [PDF]
Gestational Trophoblastic Neoplasms (GTN) are group of diseases which are known as fertilization disorders and may appear as Complete hydatidiform mole, Mole partialis, Invasive mole, Placental site trophoblastic tumor, Choriocarcinoma. Malignant disease
Nikolić Branka +5 more
doaj
Gyne-Oncology Interactive Problem-Based Cases for Postgraduate Residents
This educational resource is a series of five interactive problem-based cases that focus on the management of patients presenting with cancers of the female reproductive tract (cancer of the cervix, endometrium, vulva, ovary and gestational trophoblastic
Leslie Sadownik, Sarah Finlayson
doaj +1 more source
Fertility preservation in ovarian tumours [PDF]
A considerable number of patients with a cancer diagnosis are of childbearing age and have not satisfied their desire for a family. Despite ovarian cancer (OC) usually occurring in older patients, 3%–14% are diagnosed at a fertile age with the overall 5 ...
Bardhi, E. +8 more
core +1 more source
Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade +2 more
wiley +1 more source
The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy
The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu +7 more
wiley +1 more source
Choriocarcinoma and placental site trophoblastic tumor (PSTT) are rare varieties of gestational trophoblastic disease (GTD). PSTT alone constitutes about 1-2% of all trophoblastic tumors, which presents at early reproductive age and the serum beta-hCG ...
SetareNasiri +5 more
doaj
Is Doppler ultrasound useful for evaluating gestational trophoblastic disease?
Doppler ultrasound is a non-invasive method for evaluating vascularization and is widely used in clinical practice. Gestational trophoblastic neoplasia includes a group of highly vascularized malignancies derived from placental cells.
Lawrence H. Lin +4 more
doaj +1 more source

