Results 81 to 90 of about 8,240 (228)

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

The Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk, Joost H. N. Schuitemaker, Marijke M. Faas, Alexandra M. Smink   +3 more
wiley   +1 more source

Doença trofoblástica gestacional: conceitos atuais quanto a classificação, etiologia e patogenia. [PDF]

, 1983
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Vieira, Maricélia
core  

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

ITALIAN CANCER FIGURES - REPORT 2015: The burden of rare cancers in Italy = I TUMORI IN ITALIA - RAPPORTO 2015: I tumori rari in Italia [PDF]

, 2016
OBJECTIVES: This collaborative study, based on data collected by the network of Italian Cancer Registries (AIRTUM), describes the burden of rare cancers in Italy.
Adamo, Ms, Adorni, A, Alessi, D, Aletta, P, Amendola, V, Amodio, R, Amodio, Rosalba, Andreone, S, Angelin, T, Anghinoni, E, Annulli, Ml, Autelitano, M, Balducci, C, Baracco, M, Baracco, S, Barale, A, Barchielli, A, Battisti, W, Bella, F, Bella, Francesca, Bellatalla, C, Bellini, A, Belluardo, C, Benatti, P, Benedetto, G, Benfatto, L, Bernazza, E, Bianconi, F, Biavati, P, Bidoli, E, Birri, S, Bizzoco, S, Bizzoco, Sabrina, Bonini, A, Borciani, E, Bordini, M, Bovo, E, Bozzani, F, Braghiroli, B, Brosio, F, Brucculeri, Ma, Brunori, V, Bucalo, G, Bucchi, L, Bugliarello, E, Bulatko, A, Busco, S, Busco, Susanna, Busso, P, Buzzoni, C, Buzzoni, C., Buzzoni, Carlotta, Caiazzo, Al, Calabrese, A, Calabretta, L, Caldarella, A, Candela, G, Cannone, G, Canu, L, Caparelli, M, Cappelletti, M, Caprara, L, Carletti, N, Caroli, S, Cascio, Ma, Cascone, G, Casella, C, Casella, C, Cassetti, Tiziana, Castaing, M, Castaing, Marine, Cavalieri d'Oro, L, Cavallo, R, Cecconami, L, Celesia, Mv, Cena, T, Cercato, Mc, Cesaraccio, R, Chiesa, R, Cirilli, C, Cirilli, Claudia, Cocchioni, M, Codazzi, T, Cogno, R, Colamartini, A, Colavolpe, Af, Cometti, I, Contiero, P, Contrino, Ml, Corbinelli, A, Cordaro, C, Corti, M, Costa, A, Costarelli, D, Coviello, V, Crapanzano, G, Crocetti, Emanuele, Cuccaro, F, Curatella, S, Cusimano, R, Cusimano, Rosanna, D'Alessandro, A, D'Alò, D, Dal Cin, A, Dal Maso, L, Dal Maso, Luigino, Davini, C, De Angelis, Roberta, De Dottori, M, De Maria, V, De Santis, E, De Valiere, E, Dei Tos, Ap, Demurtas, G, Devigili, E, Di Dia, Pp, Di Felice, E, di Grazia, L, Di Gregorio, C, Di Norcia, R, Di Prima, A, Dinaro, Y, Distefano, R, Doa, N, Domati, F, Donini, M, Fabiano, S, Facchinelli, G, Faccini, F, Falcini, F, Falk, M, Fanetti, Ac, Fattoruso, S, Fedele, M, Ferrari, F, Ferretti, S, Fidelbo, M, Filiberti, Ra, Filipazzi, L, Fiore, Ar, Forgiarini, O, Frasca, G, Frassoldi, E, Fusco, M, Fusco, M, Fusco, Mario, Gabbi, C, Gada, D, Garrone, E, Gatta, Gemma, Gatti, L, Gennaro, V, Gennaro, Valerio, Gentilini, Ma, Gerevini, C, Germinetti, F, Ghilardi, S, Ghisleni, S, Giacomin, A, Giacomin, Adriano, Giavazzi, L, Gilardi, F, Giorgetti, S, Giorgi Rossi, Paolo, Giubelli, C, Giuliani, O, Giurdanella, Mc, Gola, G, Goldoni, Ca, Goldoni, Ca, Golizia, Mg, Grandi, L, Greco, A, Guarda, L, Guttadauro, A, Guzzinati, S, Iannelli, A, Ieni, A, Intrieri, T, Kaleci, S, Lando, C, Lavecchia, Am, Lazzarato, F, Le Rose, L, Leone, A, Leone, R, Lombardo, C, Lonati, F, Lucchi, S, Macci, L, Macerata, V, Madeddu, A, Maffei, S, Maghini, A, Magnani, C, Magnani, G, Magoni, M, Mallone, Sandra, Mancini, S, Mancuso, P, Mangone, L, Mangone, L, Mangone, Lucia, Manneschi, G, Mannino, R, Mannino, S, Mannino, Salvatore, Marani, E, Mariani, F, Martorana, C, Marzola, L, Maspero, S, Maule, M, Mazzei, A, Mazzoleni, G, Mazzucco, G, Melcarne, A, Merletti, F, Merlo, E, Michiara, M, Migliari, E, Minerba, S, Minicuzzi, A, Mizzi, M, Monetti, D, Morana, G, Moroni, E, Mosso, Ml, Muni, A, Mura, F, Natali, M, Negrino, L, Nemcova, L, Nicita, C, Nocera, V, Paderni, F, Pala, F, Palumbo, M, Panciroli, E, Panico, M, Pannozzo, F, Pascucci, C, Pasolini, A, Pastore, G, Patriarca, S, Pedroni, M, Perrotta, C, Pesce, P, Petrinelli, Am, Petrucci, C, Pezzarossi, A, Pezzuto, L, Piccinni, L, Pierannunzio, Daniela, Piffer, S, Pinon, M, Pinto, A, Pintori, N, Pirino, D, Pironi, V, Ponz de Leon, M, Prandi, R, Prazzoli, R, Puleio, M, Puppo, A, Quarta, F, Quattrocchi, M, Raho, Am, Ramazzotti, V, Rashid, I, Ravaioli, A, Ravazzolo, B, Ravegnani, M, Reggiani-Bonetti, L, Ricci, P, Rizzello, R, Rognoni, M, Rollo, Pc, Romanelli, A, Roncaglia, F, Roncucci, L, Rosano, A, Rossi, F, Rossi, G, Rossi, M, Rossi, Silvia, Rossini, S, Rosso, S, Rudisi, G, Ruggeri, Mg, Russo, Ag, Ruzza, Mr, Sacchettini, C, Sacchetto, L, Sacco, G, Sacerdote, C, Sala, O, Salvi, O, Sampietro, G, Santucci, C, Scheibel, M, Sciacca, S, Sciacchitano, C, Sciacchitano, S, Scuderi, T, Sechi, O, Seghini, P, Senatore, G, Sensi, F, Serraino, D, Sgargi, P, Sini, Gm, Sobrato, I, Solimene, C, Spagnoli, G, Spano, F, Spata, E, Sperduti, I, Spinosa, S, Staiti, R, Stocco, C, Storchi, C, Stracci, F, Sunseri, R, Susini, N, Sutera Sardo, A, Tagliabue, G, Tamburo, L, Tamburrino, S, Taranto, V, Tavilla, Andrea, Terracini, B, Tisano, F, Tittarelli, A, Tognazzo, S, Tognazzo, Sandro, Torrisi, A, Torrisi, A, Traina, A, Trama, Annalisa, Trapani, C, Tschugguel, B, Tumino, R, Tumino, Rosario, Usala, M, Vacirca, S, Valente, N, Valerio, O, Valla, K, Varvarà, M, Vasquez, E, Vassante, B, Vattiato, R, Vercellino, Pc, Vicentini, M, Vicentini, Massimo, Villa, M, Visoli, C, Vitale, F, Vitale, Maria Francesca, Vitale, Mf, Vitali, B, Vitali, Me, Vitarelli, S, Vittadello, F, Zanchi, A, Zanetti, R, Zani, G, Zanier, L, Zappa, M, Zarcone, M, Ziino, Ac, Zorzi, M, Zucchetto, A, Zucchi, A   +374 more
core   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu, Yanjiao Huang, Chenyue Hu, Wenli Ding, Zhenwei Pu, Qiang Li, Zhiliang Xu   +6 more
wiley   +1 more source

CGB5 expression is independently associated with poor overall survival and recurrence‐free survival in patients with advanced gastric cancer

Cancer Medicine, 2018
The human CGB5 gene encodes chorionic gonadotropin (hCG)β 5, which is aberrantly expressed in trophoblastic neoplasm and in some non‐trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth.
Yuxin Yang, Yonghong Shi, Yanjuan Hou, Ying Lu, Jinliang Yang   +4 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, Volume 20, Issue 5, Page 1220-1236, May 2026.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

Advanced Science, Volume 13, Issue 27, 13 May 2026.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao, Chuyu Yun, Hongying Shan, Yuqian Wang, Xiunan Chen, Weisi Lian, Tianliu Peng, Min Zhao, Xunsi Qin, Kailun Hu, Ping Zhou, Yue Wang, Yanli Pang, Rong Li   +13 more
wiley   +1 more source

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu, Wen‐Juan Wang, Ting‐Ting Zhang, Qi‐Chong Yang, Haliminai Dilimulati, Song‐Tao An   +5 more
wiley   +1 more source