Results 151 to 160 of about 3,985 (199)

Malignant trophoblastic neoplasms with different modes of origin

Cancer Genetics and Cytogenetics, 1995
The genetic origin of 24 trophoblastic neoplasms was determined using PCR polymorphisms. Based on pregnancy history, these tumors included nine postmolar trophoblastic tumors, 12 tumors preceded by live birth or abortion, and three nongestational tumors.
Hitoo Nakano, Toshiro Imamura, Norio Wake, Noriaki Sakuragi, Masahiro Higashi, Seiichiro Fujimoto, Toshiharu Kamura, Takahiro Arima   +7 more
openaire   +3 more sources

Gestational trophoblastic neoplasms: Morphologic considerations

Human Pathology, 1977
Abnormal trophoblastic proliferation is the hallmark of a spectrum of lesions constituting the gestational trophoblastic neoplasms. Rapid proliferation, infiltration, vascular invasion, hematogenous dissemination, and spontaneous regression are features of both normal and neoplastic trophoblast.
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Worldwide Controversies in Gestational Trophoblastic Neoplasms

International Journal of Gynecology & Obstetrics, 1977
ABSTRACTThis article reviews worldwide controversies concerning gestational trophoblastic neoplasms (hydatidiform mole, invasive mole, and choriocarcinoma). The epidemiology, endocrinology, histopathologic grading, classification, diagnosis, treatment, management and follow‐up (including chemotherapy, irradiation, and immunotherapy) of gestational ...
openaire   +3 more sources

Gestational trophoblastic neoplasm of the uterus: MR assessment.

Radiology, 1986
Magnetic resonance (MR) imaging characteristics of uterine gestational trophoblastic neoplasia were prospectively studied in nine women (aged 21-58 years). MR imaging was done at the time of initial clinical diagnosis, after each of the first two cycles of chemotherapy, and 6-9 months after initiation of chemotherapy.
Barbara E. Demas, C A Braga, Madeleine R. Fisher, Hedvig Hricak, M L Winkler   +4 more
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Metastatic Adnexal Trophoblastic Neoplasm

Journal of Computer Assisted Tomography, 1988
We report a case of pathologically proven metastatic trophoblastic neoplasm involving the adnexa which occurred after dilatation and curettage and chemotherapy. Duplex doppler ultrasound demonstrated increased vascularity in the adnexa. Angiography was sensitive but did not decisively distinguish between tumor in the adnexa and arteriovenous fistula in
Monica Santamaria, Chusilp Charnsangavej, Jeffrey T. Hall, William L. Kraft, David R. Mirich   +4 more
openaire   +3 more sources

The Role of Methotrexate in the Chemotherapy of Gestational Trophoblastic Neoplasms

1984
The successful use of methotrexate in metastatic choriocarcinoma in 1956 (1) marked a milestone in the history of curative cancer chemotherapy. The survival of patients with widespread disease increased from 10% in the pre-chemotherapy era (2) to 47% in 1961 (3), 74% in 1965 (4), and to about 90% at the present time (5–7).
A. Sobrero, Joseph R. Bertino
openaire   +3 more sources

Gestational Trophoblastic Neoplasms: The Role of Chemotherapy and Surgery

Surgical Clinics of North America, 1978
Current methods of diagnosis and treatment are reviewed. Special attention is directed to the diagnostic and therapeutic problems associated with the presence of brain metastases.
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First World Congress on Trophoblast Neoplasms

1984
Circulating immune complex (CIC) levels were measured by a polyethylene glycol turbidity assay in patients with molar pregnancy to investigate the relationship between CIC and trophoblastic tumor burden. At the time of presentation, CIC values were in normal range in 27 (87%) of 31 patients with molar pregnancy. Three of the four patients who presented
R. S. Berkowitz, S. J. Lahey, G. Steele, A. A. Rayner, M. L. Rodrick, D. P. Goldstein, R. Harahap, R. A. Pattillo, S. Sasaki, K. P. Katayama, M. Roesler, R. F. Mattingly, D. P. Goldstein, R. S. Berkowitz, P. K. Zucker, M. R. Bernstein, H. Salari, V. Partovie, M. W. Shin, Ch. V. Rao, R. O. Hussa, F. R. Carman, M. L. Rinke, C. L. Cook, M. A. Yussman, H. Zakut, A. Ludomirsky, L. A. Cole, S. K. Sutphen, R. O. Hussa, R. A. Pattillo, S. J. Kim, B. C. Kang, J. K. Jung, J. W. Lee, C. B. Sekadde-Kigondu, J. K. G. Mati, A. E. Mokohka, F. B. Fongoh, R. M. Lequin, T. Tanaka, H. Ito, T. Hosokawa, R. A. Elegbe, R. O. Hussa, R. A. Pattillo, I. O. Damole, R. G. Hoffmann, W. Finlayson, W. B. Jones, G. W. Stanimir, J. L. Lewis, R. S. Berkowitz, D. P. Goldstein, J. Birnholz, D. P. Goldstein, R. S. Berkowitz, M. R. Bernstein, C. T. Hsu, M. Sarram, H. Baja-Panlilio, A. M. Lopez, I. C. Huy, E. J. Aartsen, F. B. Lammes, M. J. ten Kate Booy, Heung Tat Ng, V. Partovi, H. Salari, G. H. Nassirai, Djamhoer Martaadisoebrata   +70 more
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Gestational trophoblastic neoplasms: Morphologic correlates of therapeutic response

American Journal of Obstetrics and Gynecology, 1978
GTN were evaluated histologically in reference to biologic behavior and response to chemotherapy. GTN requiring more intensive, multiple drug chemotherapy usually exhibited increased mitotic activity, nuclear atypias, compact growth of cytotrophoblast, and little maturation, as compared to lesions that responded more favorably.
Donald P. Goldstein, Shirley G. Driscoll, Liane Deligdisch   +2 more
openaire   +3 more sources

Gestational trophoblastic neoplasms in homozygous twins.

Obstetrics and gynecology, 1982
The occurrence of gestational trophoblastic disease in homozygous twins is described. The correlation between this finding and current genetic hypotheses on the pathogenesis of hydatidiform mole is considered.
C. La Vecchia, S. Franceschi, M. Fasoli, C. Mangioni   +3 more
openaire   +2 more sources