Molecular genotyping of placental site and epithelioid trophoblastic tumours; female predominance [PDF]
OBJECTIVE: To investigate a large series of placental site trophoblastic tumours (PSTT) and epithelioid trophoblastic tumours (ETT) and determine the relationship between their development and the type and sex of both the immediately antecedent and ...
Fisher, RA+4 more
core +1 more source
Exploring the interdependencies of research funders in the UK [PDF]
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P+13 more
core +1 more source
Brain metastases of choriocarcinoma: A report on two cases [PDF]
Introduction. Gestational trophoblastic diseases (GTD) are a spectrum of tumors with a various of biological behavior and potential for metastases. It consists of hydatiform mole, invasive mole, choriocarcinoma and placental site trophoblastic tumor ...
Grujičić Danica+4 more
core +1 more source
A clinicopathological study of gestational trophoblastic disease in a tertiary care centre of southern Assam [PDF]
Background: Gestational trophoblastic disease (GTD) covers a wide spectrum of benign and malignant conditions that arise from pregnancies with abnormal trophoblastic tissue development. It is a source of significant morbidity as well as increased risk of
Deka, Monoj K.+2 more
core +2 more sources
p21(WAF1/CIP1) expression in gestational trophoblastic disease: correlation with clinicopathological parameters, and Ki67 and p53 gene expression [PDF]
Background--The p21(WAF1/CIP1) gene mediates growth arrest by inhibiting G 1 cyclin dependent kinases and has been considered as a downstream effector of the tumour suppressor gene p53.
Cheung, ANY+4 more
core +2 more sources
Accuracy of computerized tomography in determining hepatic tumor size in patients receiving liver transplantation or resection [PDF]
Computerized tomography (CT) of liver is used in oncologic practice for staging tumors, evaluating response to treatment, and screening patients for hepatic resection.
Bron, K+8 more
core +1 more source
The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts [PDF]
The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of cell proliferation, differentiation, and cellular stress response.
A Fotovati+67 more
core +4 more sources
Constitutional trisomy 8 as first mutation in multistep carcinogenesis: clinical, cytogenetic, and molecular data on three cases. [PDF]
Three patients, with constitutional trisomy 8 mosaicism (CT8M), who developed a malignancy are reported. The diagnoses were refractory anaemia, acute lymphoblastic leukaemia, and idiopathic myelofibrosis.
ADDIS P.+11 more
core +1 more source
Placental site trophoblastic tumor: a case report and review of the literature [PDF]
We present a case of a gravida 1 para 1 woman, who presented with an 11- month history of amenorrhea after cesarean delivery. The patient was taking birth control pills at the time of presentation.
Cunha, Teresa Margarida+2 more
core +1 more source
Pulmonary function in patients with trophoblastic disease treated with low-dose methotrexate [PDF]
The Sheffield Trophoblastic Disease Centre treats about 25 patients with persistent trophoblastic disease each year. A total of 75% of patients are classified as low risk according to the Charing Cross Hospital prognostic scoring system and receive ...
Coleman, R. E.+5 more
core +2 more sources