Hypothesis on the possible relevance of the immunogenic cell death in the treatment of gestational trophoblastic neoplasms [PDF]
The genetic background and the antigenic landscape of cancer cells play a critical role in the response to immunotherapies. A high tumor antigenicity, together with an increased adjuvanticity potentially induced by a peculiar type of cell death, namely ...
G. Frega +5 more
doaj +2 more sources
PATIENTS WITH METASTATIC GESTATIONAL TROPHOBLASTIC NEOPLASMS AND NO GYNECOLOGICAL SYMPTOMS [PDF]
Early recognition of Gestational Trophoblastic Neoplasm (GTN) will maximize the chances of cure with chemotherapy but some patients present with many different symptoms months or even years after the causative pregnancy making diagnosis difficult ...
F. Ghaemmaghami T. Ashraf Ganjoie
doaj +2 more sources
AIMS OF THE STUDY The European Society of Medical Oncology (ESMO) recommends that countries should have reference centres to provide adequate diagnosis and treatment of gestational trophoblastic disease.
Aurore Fehlmann +12 more
doaj +2 more sources
Epithelioid Trophoblastic Tumour: A Case with Genetic Linkage to a Child Born over Seventeen Years Prior, Successfully Treated with Surgery and Pembrolizumab [PDF]
Epithelioid trophoblastic tumours are rare neoplasms showing differentiation towards the chorion leave-type intermediate cytotrophoblast, with only a handful of cases being reported in the literature.
David Pisani +7 more
doaj +2 more sources
Uterine choriocarcinoma diagnosed 11 years after menopause: A case report
Background: Gestational trophoblastic neoplasms (GTNs) encompass a wide spectrum of diseases, of which choriocarcinoma is one of the most common. Choriocarcinoma occurs mainly in relation to pregnancy and rarely after the menopause.
Georges El Hasbani +7 more
doaj +2 more sources
Machine learning-driven survival prediction in gestational trophoblastic neoplasms: a focus on PSTT and ETT prognosis [PDF]
IntroductionThe clinicopathological characteristics and prognosis of placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT) have not been well summarized.
Sakhr Alshwayyat +6 more
doaj +2 more sources
Recurrent pneumothoraces caused by a high-grade lung carcinoma with trophoblastic differentiation: a case report [PDF]
Gestational trophoblastic neoplasms are tumors that occur during pregnancy, while non-gestational trophoblastic tumors have a similar histology but are present outside of gestation. Literature reports several cases of non-gestational trophoblastic tumors
Márton Csaba +17 more
doaj +2 more sources
A case report: false hCG trail: dysgerminoma imitates gestational trophoblastic disease [PDF]
Ovarian malignant germ cell tumors (MOGCTs) represent approximately 5% of all ovarian malignancies. However, in women aged 10 to 30, they account for up to 70% of ovarian neoplasms and may occasionally occur bilaterally.
Anna Babkova, PhD +7 more
doaj +2 more sources
We present a complicated case of recurrence of gestational trophoblastic neoplasms (GTN), mixed ETT and choriocarcinoma at an abdominal cesarean scar. This tumor consisted of typical morphologic and immunophenotypic features of ETT and choriocarcinoma ...
Chunyan Zeng +4 more
doaj +2 more sources
As epithelioid trophoblastic tumor (ETT) shares similar clinical features with other gestational trophoblastic neoplasms (GTNs), it is likely to be clinically misdiagnosed and subsequently treated in an improper way.
Jiale Qin +9 more
doaj +2 more sources

