Results 41 to 50 of about 99,435 (247)

Gestational trophoblastic tumours and non-neoplastic trophoblastic lesions: morphology and immunocytochemistry to refine the diagnosis [PDF]

open access: yes, 2019
Gestational trophoblastic disease (GTD) is generally subclassified into hydatidiform moles (HM), Gestational trophoblastic tumours (GTTs) and non-neoplastic trophoblastic lesions. GTT represent a spectrum of neoplasms that originate from the extravillous
Sebire, NJ, Kaur, B
core   +1 more source

Uterine rupture secondary to undiagnosed placental site trophoblastic tumor: case report

open access: yes, 2022
Placental site trophoblastic tumor is a rare and malignant form of gestational trophoblastic disease. Its incidence rate is 1/50.000-100.000 pregnancies and accounts for less than 3% of all cases of gestational trophoblastic disease.
Arthur Antolini Tavares   +3 more
core   +1 more source

Molecular and immunohistochemical characteristics of complete hydatidiform moles

open access: yesBalkan Journal of Medical Genetics, 2017
Molar pregnancy is a gestational trophoblastic disease that belongs to the category of precancerous lesions. On the other end of the spectrum are gestational trophoblastic neoplasms such as invasive mole, choriocarcinoma, placental site trophoblastic ...
Kubelka-Sabit KB   +6 more
doaj   +1 more source

Gestational Trophoblastic Disease with Pulmonary and Cerebral Metastasis: Can Fluorodeoxyglucose Positron Emission Tomography Really Detect Cranial Metastatic Disease ?

open access: yes, 2016
Gestational trophoblastic neoplasms (GTN) originate from placental tissue and usually metastasizes because of its propensity for early vascular invasion. Intracranial metastases are relatively uncommon.
Serkan Uysal   +4 more
core   +1 more source

High risk gestational trophoblastic diseases: Diagnosis and primary management with EMACO chemotherapy [PDF]

open access: yes, 2015
Gestational trophoblastic disease (GTD) is characterized by abnormal proliferation of pregnancy associated trophoblastic tissue with malignant potential.
Kadam R. Priyanka, Dave S. Pariseema
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Confusing trophoblastic lesion (placental site nodule): case report [PDF]

open access: yes, 2014
İnönü Üniversitesi Sağlık Bilimleri Dergisi 2014; 3 (2): 26-27 ss.Plasental site nodül, genellikle üreme çağındaki kadınların, küretaj materyallerinde, serviks biyopsilerinde ve histerektomi materyallerinde, rastlantısal olarak karşımıza çıkar ...
Azatçam, Meltem, Altun, Eren
core   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma. [PDF]

open access: yesPLoS ONE, 2017
The uterine corpus represents the most common site for tumour development in the female genital system. Uterine neoplasms are categorised as epithelial, mesenchymal, mixed epithelial-mesenchymal or trophoblastic tumours. In this study we employed a mouse
Laura P Brandt   +5 more
doaj   +1 more source

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

open access: yesAdvanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen   +10 more
wiley   +1 more source

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