Results 121 to 130 of about 99,435 (247)
Hypoxia‐Driven CA2 Promotes Trophoblast Dysfunction in Preeclampsia
CA2 is upregulated in preeclampsia and impairs trophoblast function by suppressing VEGFA under hypoxia/HIF‐1α signaling. LNP‐mediated CA2 silencing improves placental structure and fetal outcomes, highlighting CA2 as a promising therapeutic target for PE.
Lujiao Chen +7 more
wiley +1 more source
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source
Although interest in pancreatic pathology is very high in the radiological and gastroenterological communities, it is still the case that less is known about pathology of the pancreas than about liver pathology, for example.
Valentina Ciaravino +11 more
core +1 more source
Placental site trophoblastic tumor of the uterus: a mistaken diagnosis [PDF]
Placental site trophoblastic tumor (PSTT) is the rarest form of Gestational Trophoblastic Neoplasia (GTN). We present this case of uterine PSTT to illustrate the difficulties in the diagnosis of this tumor and how this led to delay in its appropriate ...
Talwar, Divya +5 more
core
The Role of Noncoding RNA in MGMT‐Positive Glioblastoma: A Narrative Review
ABSTRACT Glioblastoma (GBM) is the most aggressive primary malignant tumor of the central nervous system and is characterized by rapid progression, frequent recurrence, and poor survival outcomes. The current standard of care, comprising maximal safe surgical resection followed by radiotherapy with concomitant and adjuvant temozolomide (TMZ), has ...
Junfeng Zhao +6 more
wiley +1 more source
The clinicopathological features of intermediate trophoblastic tumor in the pineal region
Objective To evaluate the clinicopathological features of intermediate trophoblastic tumor (ITT) in the pineal region. Methods A retrospective study was performed to analyse the diagnostic and therapeutic process of 1 case with ITT in the pineal region ...
Yun⁃xiang ZHANG +4 more
doaj
GRP78 expression in trophoblastic cells.
A- GRP78 mRNA from control (CTRL) and preeclamptic (PE) trophoblastic cells was quantified by qPCR and normalized to cyclophlin A. B- GRP78 expression from control (CTRL) and preeclamptic (PE) trophoblastic cells was quantified by Cell-ELISA. C- Relative
Olivier Irion (228937) +6 more
core +1 more source
Fifteen new actinomycin analogs, named actinomycins H1–H15, are identified from S. polyantibioticus S4D258. Actinomycins H7–H15 are truncated actinomycin analogs. Actinomycins H1–H6 and H9 exhibit significant antiproliferative activities against both MDA‐MB‐231 and 4T1 TNBC cells.
He Pang +4 more
wiley +1 more source
Elevation of hCG in CSF in pinealoblastoma: a pitfall rescued by pathological examination
Human chorionic gonadotropin (hCG) is a hormone that may be abnormally secreted in several tumour types, including intracranial germ cell tumours. In pineal region tumors, hCG is a key tumor marker.
François Bouille +7 more
doaj +1 more source
Extensive trophoblastic differentiation in case of an endometrial carcinoma
Trophoblastic differentiation of endometrial carcinoma is extremely rare, till date 18 cases reports are there in the literature. A 68-year-old postmenopausal female presented with abnormal vaginal bleeding.
Nishant Sagar +5 more
core +1 more source

