Results 141 to 150 of about 99,435 (247)

Gestational trophoblastic neoplasm [PDF]

, 2020
openaire   +1 more source

Not Whether, but in Whom: Reframing Antibody–Drug Conjugate Sequencing in Metastatic Breast Cancer

Cancer Innovation, Volume 5, Issue 5, October 2026.
Armando Orlandi
wiley   +1 more source

KRAS Mutations in Cancers: From Undruggable Dilemma to Precision Medicine

MedComm, Volume 7, Issue 10, October 2026.
KRAS‐mutant cancers are therapeutically shaped by both allele identity and tumor context. Direct KRAS inhibition has achieved the greatest clinical success in KRAS G12C‐mutant NSCLC, whereas colorectal cancer often requires EGFR cotargeting and pancreatic cancer remains constrained by stromal and metabolic barriers. Shared resistance mechanisms include
Jiaying Cai, Yimin Wu, Xing Jia, Li Yang, Wenjun Yang, Weishan Lu, Zhiye Huang, Yang Pan, Zixuan Fei, Junnan Ru, Jiazheng Zhao, Jue Shen, Taobo Luo, Da Chen, Haihong Yu, Haihan Deng, Jian Zeng, Wenmei Jiang, Leilei Wu   +18 more
wiley   +1 more source

Small Proteoglycans, Big Impact: Decorin, Biglycan, and Asporin in Musculoskeletal Tissue Health and Disease

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT The extracellular matrix (ECM) is a dynamic and information‐rich network that integrates structural support with biochemical and mechanical signaling. Among its key regulatory components are the Small Leucine‐Rich Proteoglycans (SLRPs), a family of matrix molecules that coordinate extracellular architecture with cell signaling.
Alessandra Leone, Zsuzsa Jenei‐Lanzl, Frank Zaucke   +2 more
wiley   +1 more source

[Epithelioid trophoblastic tumour]

, 2010
Epithelioid trophoblastic tumour is a rare gestational trophoblastic disease. The diagnosis is based on microscopic morphology and immunohistochemical staining.
Eiholm, Susanne, Langhoff, Jill Levin, Palle, Connie   +2 more
core   +1 more source

Genital Tract and Circulating CD8+ T Cell Phenotypes Vary Across the Menstrual Cycle

American Journal of Reproductive Immunology, Volume 96, Issue 4, October 2026.
ABSTRACT Problem The menstrual cycle consists of two main phases: the follicular phase, characterized by rising estradiol and low progesterone, and the luteal phase, marked by elevated progesterone following ovulation. Changes in sex hormones have profound physiological effects, yet their impact on immunity remains poorly understood.
Irene Cruz Talavera, Katherine K. Thomas, Jessica B. Graham, Jessica L. Swarts, Sarah C. Vick, Finn MacLean, Nicole B. Potchen, Lakshmi Warrier, Adino Tesfahun Tsegaye, Sean M. Hughes, Florian Hladik, Bhavna H. Chohan, Kenneth Ngure, Nelly Mugo, Jairam R. Lingappa, Jennifer M. Lund, for the Kinga Study Team   +16 more
wiley   +1 more source

Negotiating Reproductive Identity After Cancer: A Qualitative Systematic Review of Female Survivors' Post‐Treatment Fertility Experiences

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Background Fertility concerns are common among female cancer survivors and are shaped by sociocultural influences that extend beyond biomedical outcomes. Previous systematic reviews have consolidated evidence on fertility‐related distress but have tended to operate within clinical or descriptive frameworks.
Yijun Wang, Margo Louise Turnbull, Jeffry Oktavianus, Xiaoyan I. Wu   +3 more
wiley   +1 more source

A case of placental polyp after normal vaginal delivery

Journal of Research in Medical Sciences, 2014
Placental polyp is retained placental tissue within the endometrial cavity, which forms a nidus for inflammation and bleeding. There are very few reported cases of the clinical placental polyp. Here, we report a case of 34-year-old G4L3Ab1 woman with the
Fariba Behnamfar, Fereshteh Mohammadi Zadeh, Leila Hashemi   +2 more
doaj  

Metformin Inhibits Trophoblast Ferroptosis by Suppressing ATF2 and Activating the PI3K/Akt/Nrf2 Pathway to Improve Gestational Diabetes Mellitus

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Metformin suppresses ATF2 expression, activating the PI3K/Akt pathway and promoting Nrf2 nuclear translocation. This upregulates GPX4, inhibiting ferroptosis in trophoblast cells. Erastin blocks system Xc−, depleting GSH and promoting ferroptosis. LY294002 and ML385 inhibit the pathway, validating the mechanism.
Dandan Xia, Yuhui Zhang, Wenjie Liu, Siyu Li, Chenying Zhang, Guangtong She, Huiyan Wang   +6 more
wiley   +1 more source

Ectopic β-hCG-Expressing Hepatic Neoplasm with Cutaneous Metastasis in a Young Postpartum Woman: A Case Report and Literature Review

International Journal of Women's Health
Yameng Zheng,1 Meiqin Yang,2 Wen Xu,1 Pintong Huang1 1Department of Ultrasound, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2Department of Ultrasound, Jiande First People’s Hospital ...
Zheng Y, Yang M, Xu W, Huang P
doaj